General or Spinal Anesthesia for Cesarean Delivery

NCT05727449 | Completed

• 1 other identifier: IstanbulMU Cesarean Delivery
• Study Type: observational
• Target: 862
• Locations: 1 country
• Sites: 1

Brief Summary

During the cesarean deliveries, one of the anesthesia techniques, regional anesthesia or general anesthesia (GA) is prefered. Spinal anesthesia (SA) is preferred among the regional anesthesia methods because the onset of anesthesia is faster and muscle relaxation is more suitable for cesarean section anesthesia. Although both methods have advantages and disadvantages, the anesthesia method to be chosen may vary depending on the condition of the mother and fetus. The goal of this retrospective clinical trial is to compare general and spinal anesthesia in cesarean deliveries. The main questions it aims to answer are:

• Are the anesthesia techniques effect maternal outcome?
• Are the anesthesia techniques effect fetal outcome?

Conditions

Anesthesia for Cesarean Delivery

Outcome Measures

Primary Outcomes (9)

• Apgar 1st minute score

  The Apgar score is based on a total score of 1 to 10. The higher the score, the better the baby is doing after birth. A score of 7, 8, or 9 is normal and is a sign that the newborn is in good health

  1st minute after birth

• Apgar 5th minute score

  The Apgar score is based on a total score of 1 to 10. The higher the score, the better the baby is doing after birth. A score of 7, 8, or 9 is normal and is a sign that the newborn is in good health

  5th minute after birth

• Umbilical Cord Blood pH

  pH values from umblical cord blood sampling

  at the time of birth

• Umbilical Cord Blood PCO2

  mmHg

  at the time of birth

• Umbilical Cord Blood HCO3

  mEq/L

  at the time of birth

• Umbilical Cord Blood Lactate

  mmol/L

  at the time of birth

• Umbilical Cord Blood Base Excess

  mEq/L

  at the time of birth

• need for neonatal intensive care

  need for neonatal intensive care

  up to 24 hours

• need for maternal intensive care

  need for maternal intensive care

  up to 24 hours

Study Arms (2)

General Anesthesia for Cesarean Delivery

Procedure: General Anesthesia

Spinal Anesthesia for Cesarean Delivery

Procedure: Spinal Anesthesia

Interventions

General Anesthesia PROCEDURE

General Anesthesia was intruduced for Cesarean Delivery

General Anesthesia for Cesarean Delivery

Spinal Anesthesia PROCEDURE

Spinal Anesthesia was intraduced for Cesarean Delivery

Spinal Anesthesia for Cesarean Delivery

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The pregnant women and their babies in 01.01.2019 - 31.12.2019.

You may qualify if:

• The pregnant women who delivered with cesarean section

You may not qualify if:

• The pregnant women who delivered with spontan vaginal delivery.

Sponsors & Collaborators

• Istanbul Medeniyet University: lead

Study Sites (1)

Istanbul Medeniyet University

Istanbul, 34730, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Anesthesia, General; Anesthesia, Spinal

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia; Anesthesia, Conduction

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: January 22, 2023
• First Posted: February 14, 2023
• Study Start: January 1, 2019
• Primary Completion: December 31, 2019
• Study Completion: January 1, 2021
• Last Updated: February 22, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)