Effect of Iodine Deficiency on Periodontitis

NCT05724251 | Completed

• 1 other identifier: 9375
• Study Type: observational
• Target: 73
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to compare urine iodine levels of participants with/without periodontitis. The main question it aims to answer is there a relationship between iodine levels of urine and periodontitis. Participants will give urine samples without any intervention.

Conditions

Periodontal Diseases; Periodontitis; Iodine Deficiency; Periodontitis, Adult

Keywords

periodontitis; Iodine Deficiency

Outcome Measures

Primary Outcomes (1)

• iodine deficiency

  iodine level of participants

  0-1 hours of the diagnosis

Study Arms (2)

Healthy

participants without periodontitis

Other: healthy

periodontitis

participants with stage-3 periodontitis

Other: periodontitis

Interventions

healthy OTHER

no intervention

Healthy

periodontitis OTHER

no intervention

periodontitis

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

individuals who referred to Atatürk University, Department of Periodontology

You may qualify if:

• Individuals should not have any systemic disease that may or may not require medication, including salivary gland pathologies, and not particularly thyroid organ pathologies.
• Individuals have not been continuously treated with anti-inflammatory, antioxidant or similar drugs in the last 6 months,
• Individuals have not received periodontal treatment until 6 months ago,
• Individuals must have at least 14 teeth
• Patients diagnosed with stage 3 periodontitis

You may not qualify if:

• Having a systemic disease such as cardiovascular, diabetes, hypertension, thyroid organ pathologies, chronic kidney failure
• Being pregnant/breastfeeding
• Being on medication for any reason
• Being a smoker/tobacco user
• Having another periodontal disease other than periodontitis
• Having a chronic inflammatory disease (COPD, asthma)

Sponsors & Collaborators

• Ataturk University: lead

Study Sites (1)

Atatürk University

Erzurum, 25240_, Turkey (Türkiye)

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

urine of participants

MeSH Terms

Conditions

Periodontal Diseases; Periodontitis; Chronic Periodontitis

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• DİDEM ÖZKAL EMİNOĞLU

  Ataturk University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: February 2, 2023
• First Posted: February 13, 2023
• Study Start: October 30, 2021
• Primary Completion: October 30, 2022
• Study Completion: November 30, 2022
• Last Updated: February 13, 2023

Record last verified: 2023-02

Locations

TU (1)