Evaluation of Pulp Response to Castor Oil

NCT05723900 | Completed

• 1 other identifier: #R-PED-10-22-6,
• Study Type: interventional
• Target: 31
• Locations: 1 country
• Sites: 1

Brief Summary

The present study was conducted to evaluate and compare pulp response to Castor oil versus Formocresol as Pulpotomy Medicaments in Primary Teeth

Conditions

Pulp Response to Castor Oil

Outcome Measures

Primary Outcomes (2)

• The degree of pulp inflammation using score.

  The degree of pulp inflammation using scores from 0 to 5 , 0 mean no inflammation ,5 mean abscess formation . Measurement the effect of the castor oil as pulp medicament in treated teeth which subjected to decalcification procedure for histological evaluation under light microscope

  2 weeks to 3 months

• The presence or absence of dentin chips formation by using scores 0 or 1.

  The presence or absence of dentin chips formation by using scores 0 or 1. Measurement the effect of the castor oil as pulp medicament in treated teeth which subjected to decalcification procedure for histological evaluation under light microscope

  2 weeks to 3 months

Study Arms (2)

Castor oil

EXPERIMENTAL

Castor oil applied to one side of the selected primary canine

Drug: Castor oil

Formocresol

EXPERIMENTAL

Formocresol applied to other side

Drug: Formocresol

Interventions

Castor oil DRUG

Procedure :pulpotomy procedure and histological evaluation. A sample of sixty two primary teeth from thirty healthy cooperative children of both sexes who were between 7-9 years and referred to Pediatric Dentistry Department. Two sound teeth without pulpotomy procedure were extracted and subjected to histological procedures to examine the normal pulp tissue and tissue organization (Negative control). The pulpotomy procedure was performed in sixty primary teeth (by split mouth design). group I treated with castor oil

Castor oil

Formocresol DRUG

Group II treated with formocresol

Formocresol

Eligibility Criteria

• Age: 7 Years - 9 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• healthy cooperative children with sound primary canines indicated for extraction for orthodontic reasons

You may not qualify if:

• caries primary canines Presence of systemic pathology

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Faculty of dentistry

Tanta, Egypt

Location

MeSH Terms

Interventions

Castor Oil; formocresol

Intervention Hierarchy (Ancestors)

Fats, Unsaturated; Fats; Lipids; Plant Oils; Oils; Plant Preparations; Biological Products; Complex Mixtures

Study Officials

• shomaa Mostafa Hadwa, PHD

  Tanta University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer in pediatric dentistry department faculty of dentistry tanta university

Study Record Dates

• First Submitted: January 22, 2023
• First Posted: February 13, 2023
• Study Start: September 15, 2022
• Primary Completion: October 1, 2022
• Study Completion: December 15, 2022
• Last Updated: February 13, 2023

Record last verified: 2022-10

Locations

EG (1)