NCT05013151

Brief Summary

Finding a natural and efficient method to improve the chance of entering spontaneous labor beyond 39 weeks of gestation will address both the medical necessity and the will of many parturients to avoid medical interventions. In this study we aim to evaluate the effect of dates and castor oil on the initiation of spontaneous labor in primigravida parturients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
450

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 17, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 19, 2021

Completed
5 days until next milestone

Study Start

First participant enrolled

August 24, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2022

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2022

Completed
Last Updated

August 19, 2021

Status Verified

August 1, 2021

Enrollment Period

5 months

First QC Date

August 17, 2021

Last Update Submit

August 18, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rates of spontaneous entry into labor

    Rate of women who will enter labor spontaneously without intervention

    2 weeks after enrollment

Secondary Outcomes (1)

  • Cervical ripening- Bishop score

    2 weeks after enrollment

Study Arms (3)

Date consumption

EXPERIMENTAL

Consumption of 6 dates a day until 41 weeks of gestation

Dietary Supplement: Dates

Castor oil consumption

EXPERIMENTAL

One time consumption of 60 CC of Castor oil

Dietary Supplement: Castor oil

Control Group

NO INTERVENTION

Interventions

DatesDIETARY_SUPPLEMENT

Consumption of 6 dates a days until 41 weeks of gestation

Date consumption
Castor oilDIETARY_SUPPLEMENT

One time consumption of 60 CC Castor oil

Castor oil consumption

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Pregnant women who come to the obstetrical emergency department for normal check up between 39+4 and 40+2 weeks of gestation
  • Primipara
  • Bishop cervical score below 5
  • Low risk pregnancy
  • Singleton pregnancy
  • Vertex presentation
  • Women who haven't consumed dates over once a week in month prior the checkup and haven't consumed castor oil prior to enrollment.

You may not qualify if:

  • Any medical indication for labor induction
  • Regular contractions
  • Premature rupture of membranes
  • Women who consumed dates over once a week in month prior the checkup or consumed castor oil prior to enrollment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Carmel Medical Center

Haifa, Israel

Location

MeSH Terms

Interventions

Chronology as TopicCastor Oil

Intervention Hierarchy (Ancestors)

TimePhysical PhenomenaFats, UnsaturatedFatsLipidsPlant OilsOilsPlant PreparationsBiological ProductsComplex Mixtures

Study Officials

  • Lena Sagi-Dain, MD

    Lady Davis Carmel Medical Center

    STUDY DIRECTOR

Central Study Contacts

Nir Kugelman, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Nir Kugelman

Study Record Dates

First Submitted

August 17, 2021

First Posted

August 19, 2021

Study Start

August 24, 2021

Primary Completion

January 30, 2022

Study Completion

February 28, 2022

Last Updated

August 19, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations