Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.
rhBMP-2
1 other identifier
interventional
32
1 country
1
Brief Summary
Effect of Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_1 hypertension
Started Dec 2021
Typical duration for phase_1 hypertension
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 6, 2021
CompletedFirst Submitted
Initial submission to the registry
December 7, 2022
CompletedFirst Posted
Study publicly available on registry
February 8, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 18, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
April 20, 2023
CompletedFebruary 8, 2023
January 1, 2023
1.3 years
December 7, 2022
January 31, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Effect of Recombinant Human Bone Morphogenetic The Primary outcome will be measuring the effect of rhBMP- 2/ACS in improving the secondary stability of dental implant by using RFA in comparison to control group.
The topical application of rhBMP-2 in the osteotomy site has an effect through improve secondary stability of the dental implant.
At the time of surgery ,all measurment (primary stability) was taken which represented the base line data.
Study Arms (1)
control group
EXPERIMENTALgroup consist of 16 patients with no protein application
Interventions
Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge .
Eligibility Criteria
You may qualify if:
- Patients have good oral hygiene.
- Systemic healthy individuals ,Age more than18 years.
- Healed edentulous area for at least 6 months after tooth extraction (delayed implant protocol).
- Patients have at least two missing teeth in the jaw (canine to 1st molar area) indicated for the dental implant.
You may not qualify if:
- Presence of systemic diseases preventing implantation.
- Previous implantation or augmentation of the same region.
- The need for additional bone augmentation procedures (such as maxillary sinus augmentation)
- Partial or total edentulous ridge associated with a severe knife-edge ridge .
- Acute infection or any pathological lesion a the implant site.
- Allergy to one of the materials to be used during operation.
- Pregnancy.
- Radiation therapy, bisphosphonate drugs , Osteoradionecrosis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Baghdad
Baghdad, Alresafa, 10011, Iraq
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Adbullah Al Abbas, B.D.S
University of Baghdad
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- NA
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- master student
Study Record Dates
First Submitted
December 7, 2022
First Posted
February 8, 2023
Study Start
December 6, 2021
Primary Completion
March 18, 2023
Study Completion
April 20, 2023
Last Updated
February 8, 2023
Record last verified: 2023-01