Dance/Movement Therapy for Bone Mineral Density in Schizophrenia

NCT05716802 | Completed DMC

• 1 other identifier: xmh123
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Fractures are common accidents for long-term hospitalized patients with schizophrenia (SZ) in psychiatric hospitals, and once they occur, patients usually endure the pain of fractures for a long time. Accumulating evidence has supported implementing dance/movement therapy (DMT) as a promising intervention for patients with SZ. However, no study has been conducted to investigate its role in balance ability and metabolic parameters in SZ. This study was designed to investigate the treatment outcome of a 12-week DMT intervention on bone mineral density, balance ability, and metabolic profile in patients with SZ using a randomized, controlled trial design.

Conditions

Schizophrenia

Outcome Measures

Primary Outcomes (1)

• Bone mineral density measurement

  The primary outcome measure was the BMD of patients recruited, which was assayed by an Erik AKDX-09W-1 bone density device (Shenzhen Ekere Electric Co.). The test was performed using the dual-energy X-ray absorptiometry method. Measurements were done at the distal end of the flexor bone of the patient's left forearm for fan beam and line scan, which were reviewed by an experienced radiologist who was blinded to the clinical and pharmacological characteristics and randomization of the patients.

  week 12

Secondary Outcomes (1)

• panss scale

  week 12

Study Arms (2)

dance/movement therapy (DMT), twice a week, 12 weeks,

ACTIVE COMPARATOR

The multiple-session DMT intervention was applied to participants twice a week as a total of 24 sessions of 60 minutes over three months. The DMT intervention protocol was developed based on the therapist's experience, the theoretical frameworks, and the DMT approach described in a previous study (Bryl and Goodill 2019).

Behavioral: dance/movement therapy

Treatment as usual (TAU), twice a week, 12 weeks,

PLACEBO COMPARATOR

The TAU group sessions were conducted by the licensed professional employed at the hospital. The patients received regular daily antipsychotic medication and supportive psychotherapy once a week. They also participated in daily activities from Monday to Friday for at least two hours each day, including indoor activities (watching TV, playing games, playing poker) and outside activities (walking and doing radio gymnastics).

Behavioral: treatment as usual

Interventions

dance/movement therapy BEHAVIORAL

dance/movement therapy plus treat as usual

dance/movement therapy (DMT), twice a week, 12 weeks,

treatment as usual BEHAVIORAL

The patients received regular daily antipsychotic medication and supportive psychotherapy once a week. They also participated in daily activities from Monday to Friday for at least two hours each day, including indoor activities (watching TV, playing games, playing poker) and outside activities (walking and doing radio gymnastics).

Treatment as usual (TAU), twice a week, 12 weeks,

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Clinical diagnosis of schizophrenia using the DSM-V;
• male veterans, aged 40 to 60 years with a disease duration of 5 years or more and a long-term hospitalization of 3 years or more;
• ability to understand Mandarin Chinese;
• legally eligible to sign an informed consent form;
• current antipsychotic medication stability for more than 2 years;
• reduced bone mass, osteoporosis, and severe osteopenia after bone density analysis;
• no comorbid serious physical illness and physical impairments and can cooperate with nurses to complete the general intensity of activity training;
• consent for pre- and post-session interviews.

You may not qualify if:

• \) substance dependence or abuse; 2) hypercalcemia and hyperuricemia; 3) history of kidney stones or renal calculi; 4) lower limb injury and motor dysfunction, and inability to complete DMT intervention for various reasons.

Sponsors & Collaborators

• Hebei Province Veterans Hospital: lead

Study Sites (1)

DMT

Baoding, Hebei, 050899, China

Location

MeSH Terms

Conditions

Schizophrenia

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Officials

• Hengyong Guan, Dr.

  Hebei Province Veterans Hospital

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 29, 2023
• First Posted: February 8, 2023
• Study Start: July 7, 2020
• Primary Completion: January 12, 2022
• Study Completion: July 12, 2022
• Last Updated: March 8, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)