REgiStry in Chinese yoUng pEople With Sudden Cardiac Death

NCT05713240 | Not Yet Recruiting DMC

• 1 other identifier: RESCUE-SCD
• Study Type: observational
• Target: 450
• Locations: 1 country
• Sites: 1

Brief Summary

The number of sudden cardiac death is up to 540,000 every year in China. Inherited cardiovascular disease is a common cause of sudden cardiac death in young people, and diseases often have the characteristics of family aggregation, so it has a huge psychological and economic burden on family members. Studying the etiology of sudden cardiac death from the molecular level under the model of precision medicine is helpful for screening patients and their relatives so as to further diagnosis, treatment and management, which has important clinical and social significance.

Conditions

Sudden Cardiac Death

Outcome Measures

Primary Outcomes (1)

• number of participants with cardiovascular deaths

  including sudden cardiac death and deaths due to heart failure and stroke

  an average of 2 years

Secondary Outcomes (3)

• number of participants with heart failure

  an average of 2 years

• number of participants with stroke

  an average of 2 years

• number of participants with myocardial infarction

  an average of 2 years

Eligibility Criteria

• Age: Up to 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Sudden cardiac death and high risk of sudden cardiac death in patients younger than 40 years of age from multiple centers in China between March 1, 2023 and March 1, 2025.

You may qualify if:

• Patients with sudden cardiac death and sudden unexplained death diagnosed according current practice guidelines.
• Patients at high risk for sudden cardiac death. (1) Family history of sudden cardiac death at a young age; （2）Successful resuscitation from cardiac arrest; （3) Implantable cardioverter defibrillator implantation after a comprehensive clinical assessment of high risk of sudden cardiac death.

You may not qualify if:

• Patients who refuse to sign the informed consent or decline follow-up.
• Patients with sudden death due to car accidents, electric shocks, drowning, fighting, carbon monoxide poisoning and other external causes.
• Patients with sudden death due to other definite causes, such as cerebrovascular accident, severe kidney disease, respiratory disease, neurological disease, etc.

Sponsors & Collaborators

• China National Center for Cardiovascular Diseases: lead

Study Sites (1)

Fuwai hospital

Beijing, Beijing Municipality, 100037, China

Location

MeSH Terms

Conditions

Death, Sudden, Cardiac

Condition Hierarchy (Ancestors)

Heart Arrest; Heart Diseases; Cardiovascular Diseases; Death, Sudden; Death; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Lei Song, MD.&phD

CONTACT

86-13810532620; clinicalfw@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Clinical Professor

Study Record Dates

• First Submitted: January 13, 2023
• First Posted: February 6, 2023
• Study Start: March 1, 2023
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2026
• Last Updated: February 6, 2023

Record last verified: 2023-02

Locations

CN (1)