NCT05712317

Brief Summary

This randomized control trial aims to compare the effects of a regular exergame-based intervention and a regular moderate-intensity endurance exercise in healthy individuals. The main questions it aims to answer are: • Is regular exergame-based training an effective intervention to improve different health and performance parameters in healthy adults? Can the exergaming intervention improve health and performance parameters similar to a moderate-intensity endurance exercise intervention? Throughout the intervention period (8 weeks), participants will participate in regular training sessions (3x/week) in an exergame called the ExerCube. Researchers will compare the effects to a control group who participates in regular (3x/week) moderate-intensity endurance exercise to see if the exergaming intervention induces similar effects on health and performance parameters.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 25, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 3, 2023

Completed
26 days until next milestone

Study Start

First participant enrolled

March 1, 2023

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2025

Completed
Last Updated

September 29, 2025

Status Verified

September 1, 2025

Enrollment Period

1.8 years

First QC Date

January 25, 2023

Last Update Submit

September 23, 2025

Conditions

Blood PressurePhysical Inactivity

Keywords

ExergamingBlood pressureEndurance performancePulse wave analysisExercise

Outcome Measures

Primary Outcomes (1)

  • Changes from baseline in maximum oxygen consumption at week 8

    Maximum oxygen consumption will be obtained during a cardiopulmonary exercise test on a bicycle ergometer using a validated metabolic cart.

    Baseline and week 8

Secondary Outcomes (3)

  • Changes from baseline in pulse wave velocity at week 8

    Baseline and week 8

  • Changes from baseline in systolic blood pressure at week 8

    Baseline and week 8

  • Changes from baseline in diastolic blood pressure at week 8

    Baseline and week 8

Other Outcomes (1)

  • Changes from baseline in body mass index at week 8

    Baseline and week 8

Study Arms (2)

Exergame Intervention

EXPERIMENTAL

8-week exergame-based intervention consisting of 3 sessions per week lasting between 20-40 Minutes. The intervention will consist of playing the game Sphery racer in the exergame called ExerCube.

Behavioral: Exergame Intervention

Moderate-intensity endurance exercise

ACTIVE COMPARATOR

8-week moderate-intensity endurance exercise consisting of 3 sessions per week lasting between 20-40 minutes. The intervention will consist of a running exercise on a treadmill or riding on a bicycle ergometer.

Behavioral: Moderate-intensity endurance exercise

Interventions

Exergame InterventionBEHAVIORAL

8-week exergame-based intervention 3x per week

Exergame Intervention
Moderate-intensity endurance exerciseBEHAVIORAL

8-week moderate-intensity endurance exercise 3x per week

Moderate-intensity endurance exercise

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy female and male adults
  • Aged 18-60 years
  • Free from acute and chronic diseases
  • Free from movement restrictions or injuries to the musculoskeletal system
  • Provided written informed consent

You may not qualify if:

  • Underlying health condition that could compromise the safety of the physical exercise
  • Were taking cardiovascular medications

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Bern

Bern, 3012, Switzerland

Location

MeSH Terms

Conditions

Sedentary BehaviorMotor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Sascha Ketelhut, Dr.

    University of Bern

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 25, 2023

First Posted

February 3, 2023

Study Start

March 1, 2023

Primary Completion

January 1, 2025

Study Completion

February 1, 2025

Last Updated

September 29, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

The data will be made available upon reasonable request from the principal investigator.

Shared Documents
STUDY PROTOCOL, ICF, CSR
Time Frame
After the intervention is over and all data is obtained.
Access Criteria
Reasonable request .

Locations

CH(1)