Effects of Tendon Neuroplastic Training (TNT) in Lateral Epicondylitis.
1 other identifier
interventional
34
1 country
1
Brief Summary
The aim of this research is to determine effects tendon neuroplastic training on strength, pain, and function in lateral epicondylitis. Randomized controlled trials will be conduct in National Institute of Rehabilitation Medicine Islamabad and Lady Reading Hospital Peshawar. The sample size is 34. The subjects will be divided in two groups, 17 subjects in tendon neuroplastic training group and 17 subjects will be assigned to conventional exercises group. Study duration is of one year. Sampling technique applied will be non-probability convenient sampling technique. Only 20-45 years old patients diagnosed with lateral epicondylitis will be included. Tools used in the study are Numeric pain scale, Dynamometer for grip strength and Patient rated tennis elbow evaluation for functional status.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2023
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2023
CompletedFirst Submitted
Initial submission to the registry
January 22, 2023
CompletedFirst Posted
Study publicly available on registry
January 31, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 20, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
February 25, 2023
CompletedMay 6, 2023
May 1, 2023
2 months
January 22, 2023
May 3, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Numeric pain Rating scale (NPRS)
The NPRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain. The common format is a horizontal bar or line
4th week
Secondary Outcomes (2)
Patient rated tennis elbow evaluation (functional status).
4th week
Dynamometer
4th week
Study Arms (2)
Group A: Tendon neuroplastic training (TNT)
EXPERIMENTALthe strength training of the wrist extensors are being done with the help of an externally pace device
Group B: Conventional treatment
ACTIVE COMPARATORstatic stretching and myofascial release on wrist extensors
Interventions
Subjects will attend physical therapy for three non-consecutive days per week for a total 4 consecutive weeks. Exercise would involve isolated flexion, extension with a dumbbell. This exercise would be paced with external audio/visual cue on smart phone using proMetronome app. Patients will listen to the sound and track the movement of metronome with the eyes. Pace of metronome will be set at 20 beats per minute such that each beat will be 3 sec apart. This will allow a 3sec concentric and 3 sec eccentric phases.4 sets of 8 repetitions would be completed with a 2-minute rest between each set. Exercise will begin with 3 pounds weight, but it would be made sure that this wouldn't cause pain during exercise (more than 5/10), gradual progression in weight to 5 pounds after 2nd weeks.
Subjects assigned to this group will undergo static stretching of Extensor carpi radialis brevis and myofascial release for 4 weeks, 3 sessions a week. Myofascial release technique will be applied for 5 minutes and 2 reptations per session
Eligibility Criteria
You may qualify if:
- Both male and female
- Age between 20-45 years
- Pain and Tenderness over the lateral epicondyle
- At least 2 of cozen's test, Maudsley's test and Mill's test will cause pain at lateral epicondylitis.
You may not qualify if:
- Open wounds
- Fracture of elbow Humerus, radius, ulna
- Surgical procedure done around the elbow joint.
- Elbow instability.
- Extensor tendon rupture.
- Symptoms of cervical radiculopathy.
- Radial nerve entrapment.
- Major upper limb surgery.
- Tumor or wound
- Compartment syndrome of anconeus muscle.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Institute of Rehabilitation Medicine (NIRM)
Islamabad, Capital, 46000, Pakistan
Related Publications (1)
Khan H, Razzaq A, Afridi A, Sheraz S, Awan WA. Innovative neuroplastic healing: tendon Neuroplastic Training role in pain alleviation and boosting strength in lateral epicondylitis: a randomized controlled trial. BMC Musculoskelet Disord. 2025 Oct 10;26(1):949. doi: 10.1186/s12891-025-08328-1.
PMID: 41073965DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Aisha Razzaq, MSPT-OMPT
Riphah International University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 22, 2023
First Posted
January 31, 2023
Study Start
January 1, 2023
Primary Completion
February 20, 2023
Study Completion
February 25, 2023
Last Updated
May 6, 2023
Record last verified: 2023-05
Data Sharing
- IPD Sharing
- Will not share