Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

NCT05694559 | Recruiting

• 2 other identifiers: 2022-0328NCI-2023-00252
• Study Type: interventional
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.

Conditions

Breast Cancer; Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• genetic risk screening tool (GRST) questionnaire

  through study completion; an average of 1 year.

Study Arms (2)

Genetic Testing and Counseling

EXPERIMENTAL

Participants will be given a saliva collection kit to collect a saliva sample for hereditary cancer and genetic testing.

Behavioral: Genetic Testing and Counseling

Screening Form

EXPERIMENTAL

Participants will complete a screening form to assess your risk of hereditary breast and colorectal cancers. You will be asked to provide your: * Name and contact information (including your address, phone number, and email) * Demographic information (including your age, race, and ethnicity) * Health insurance status * Annual household income * Personal and family history of cancer, including diagnosis and age at diagnosis

Behavioral: Screening Form

Interventions

Genetic Testing and Counseling BEHAVIORAL

Participants will complete testing

Genetic Testing and Counseling

Screening Form BEHAVIORAL

Participants will complete forms with demographics and history

Screening Form

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Any participant over 18 years old who self-identifies as Black or African-American and signs an informed consent form, also referred to as the 'Permission to Contact' form, to be part of our study.

You may not qualify if:

• None

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• MD Anderson Cancer Center

MeSH Terms

Conditions

Breast Neoplasms; Colorectal Neoplasms

Interventions

Genetic Testing; Counseling

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Intervention Hierarchy (Ancestors)

Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques; Genetic Techniques; Genetic Services; Health Services; Health Care Facilities Workforce and Services; Diagnostic Services; Preventive Health Services; Mental Health Services; Behavioral Disciplines and Activities; Community Health Services

Study Officials

• Banu Arun, MD

  MD Anderson Cancer Cneter

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Banu Arun, MD

CONTACT

713-792-2817; barun@mdanderson.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 12, 2023
• First Posted: January 23, 2023
• Study Start: November 23, 2022
• Primary Completion (Estimated): February 2, 2027
• Study Completion (Estimated): February 2, 2027
• Last Updated: February 19, 2026

Record last verified: 2026-02

Locations

US (1)