NCT05691296

Brief Summary

The study aimed to collect multi-factor information on school-age children with pre-clinical myopia, and to identify the initial factors and warning signs of myopia.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2020

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

December 25, 2022

Completed
26 days until next milestone

First Posted

Study publicly available on registry

January 20, 2023

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

May 7, 2024

Status Verified

May 1, 2024

Enrollment Period

4.7 years

First QC Date

December 25, 2022

Last Update Submit

May 5, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • The rate of new-onset myopia

    The number of new children with myopia was counted

    Through study completion, an average of 1 year

  • The changes of refractive error

    The changes of refractive error between visit time and baseline which was obtained with a computer refractometer.

    Every 6 months, up to 3 years

  • The changes of axial length

    The axial length was measured by a biological measuring instrument.

    Every 6 months, up to 3 years

Study Arms (3)

Home-school training group

EXPERIMENTAL

There was a Letter Chart Accomodative Rock Training for accommodation facility at home and school everyday. This training usually lasted 2 minutes each time.

Behavioral: Home trainingBehavioral: School training

School training group

EXPERIMENTAL

There was a Letter Chart Accomodative Rock Training for accommodation facility only at school everyday. This training usually lasted 2 minutes each time.

Behavioral: School training

No training group

NO INTERVENTION

There was no such treatment for students.

Interventions

Home trainingBEHAVIORAL

Letter Chart Accomodative Rock Training for 2 minutes each time

Home-school training group
School trainingBEHAVIORAL

Letter Chart Accomodative Rock Training for 2 minutes each time

Home-school training groupSchool training group

Eligibility Criteria

Age5 Years - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • All students in grades 1 to 4
  • Can cooperate with the examination of students

You may not qualify if:

  • Obvious strabismus and amblyopia
  • Eye diseases that affect vision, such as congenital cataracts, glaucoma, and retinal diseases
  • History of ocular surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tiajin Eye Hospital

Tianjin, Tianjin Municipality, 300020, China

Location

Related Publications (1)

  • Jonas JB, Ang M, Cho P, Guggenheim JA, He MG, Jong M, Logan NS, Liu M, Morgan I, Ohno-Matsui K, Parssinen O, Resnikoff S, Sankaridurg P, Saw SM, Smith EL 3rd, Tan DTH, Walline JJ, Wildsoet CF, Wu PC, Zhu X, Wolffsohn JS. IMI Prevention of Myopia and Its Progression. Invest Ophthalmol Vis Sci. 2021 Apr 28;62(5):6. doi: 10.1167/iovs.62.5.6.

    PMID: 33909032BACKGROUND

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 25, 2022

First Posted

January 20, 2023

Study Start

May 1, 2020

Primary Completion

December 31, 2024

Study Completion

December 31, 2024

Last Updated

May 7, 2024

Record last verified: 2024-05

Locations