NCT05689697

Brief Summary

The purpose of this study is evaluating of efficacy of innovative dietary strategy -stimulation of physiological ketosis with Liquid Technology Formula PanTrek, in patients with asthenia and or decreased tolerance to physical and\\or mental exertion. PanTrek is a liquid formula of potassium and magnesium salts of beta-oxibutiric acid, ginsenosides and rosmarinic acid.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
88

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 23, 2022

Completed
17 days until next milestone

Study Start

First participant enrolled

January 9, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 19, 2023

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2023

Completed
Last Updated

January 19, 2023

Status Verified

December 1, 2022

Enrollment Period

6 months

First QC Date

December 23, 2022

Last Update Submit

January 10, 2023

Conditions

Keywords

Physiological KetosisPanTrekAstheniaPhysical functioningMental functioningbeta-oxibutiric acid

Outcome Measures

Primary Outcomes (1)

  • Primary outcome

    Difference of changes of visual analog scale (VAS) indices between active treament and placebo groups. Minimum value - 0, maximum value - 100 scores. The higher score means the better condition. The major difference means better outcome.

    15 days

Secondary Outcomes (1)

  • indused ketosis

    15 days

Other Outcomes (4)

  • Improvement in cognitive function

    15 days

  • Improvement in visual attention and task switching.

    15 days

  • Improvement in physical function

    15 days

  • +1 more other outcomes

Study Arms (2)

Placebo group

PLACEBO COMPARATOR

Patients will recieve matched by taste and color shot of 25 ml liquid in ampules

Dietary Supplement: PanTrek

Active treatment group

EXPERIMENTAL

Patients will recieve shot of PanTrek 25 ml in anpules

Dietary Supplement: PanTrek

Interventions

PanTrekDIETARY_SUPPLEMENT

administration of exogenouse keton body

Active treatment groupPlacebo group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • informed consent
  • diagnosis of astenia and/or decreased tolerance to physical and\\or mental exertion
  • ability of patients to understand assessment procedures

You may not qualify if:

  • intollerance of components of PanTrek
  • participation in other trials

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Laboratory of psychopharmacology Research center of mental health

Moscow, 115522, Russia

Location

MeSH Terms

Conditions

Patient ParticipationAsthenia

Condition Hierarchy (Ancestors)

Patient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehaviorSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Denis Burminskiy, MD, PhD

    Mental health research center

    STUDY DIRECTOR

Central Study Contacts

Denis Burminskiy, MD, PhD

CONTACT

Allan Beniashvili, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
randomized asignment to placebo or IP group, double-blind design
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 23, 2022

First Posted

January 19, 2023

Study Start

January 9, 2023

Primary Completion

June 30, 2023

Study Completion

August 15, 2023

Last Updated

January 19, 2023

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations