Evolution of the Sensory Profile in Depression

NCT05686668 | Completed

• 1 other identifier: CHEsquirol
• Study Type: observational
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

The perception of the environment through the study of sensory awareness is important to understand the adaptive or symptomatological behaviors (e.g., withdrawal, increased activity level, stimulation seeking, etc.). Sensory processing disorders, such as hypersensitivities or hyposensitivities, have been described in people with depression using the Adolescent Adult Sensory Profile scale. In a recent study, similar results consistent with extreme sensory profiles (hypersensitivity, hyposensitivity, sensation avoidance) in adults with a major depressive disorder were observed. The evolution over time of the sensory profile in people with a depressive disorder is not known. It is currently unknown whether these extreme sensory processing profiles are stable over time or whether they may evolve with the depressive symptomatology to normalize with clinical improvement. This knowledge could have an important impact both on the symptomatological expression of the disorder, its recognition, and also on the management of the patient. The investigators aim to study the evolution over time of the sensory profile of depressed subjects hospitalized using the ASSP. The behavioral responses of individuals with sensory processing disorder may be related to the coping strategies of these individuals with their living environment. In a second step, the investigators will study the second step the sensory profile of subjects with depression according to their coping strategies, their living environment and their clinical characteristics (anxiety (anxiety, psychomotor slowing, self-esteem, anhedonia).

Conditions

Major Depressive Disorder

Keywords

Major Depressive Disorder; Adolescent Adult Sensory Profile; Sensory Profiles; Coping

Outcome Measures

Primary Outcomes (1)

• Change in Adolescent Adult Sensory Profile score

  measure a change in Adolescent Adult Sensory Profile score between he beginning of hospitalization and 3 months

  day 0 and 3 months

Secondary Outcomes (7)

• Hamilton Anxiety Rating Scale score

  day 0 and 3 months

• number of participants with psychomotor retardation

  day 0 and 3 months

• Snaith-Hamilton pleasure scale score

  day 0 and 3 months

• Coping Inventory for Stressful Situations score

  day 0

• number of participants living in country

  day 0

Study Arms (1)

AASP

Other: assessment by scales

Interventions

assessment by scales OTHER

Assessment from many scales: AASP, HARS, HDRS, CORE, EES, CISS, SHAPS at V1 Assessment from many scales: AASP, HARS, HDRS, CORE, EES, SHAPS at V2

AASP

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Hospitalized poeple for a major depressive disorder

You may qualify if:

• Male or female, 18 to 65 years of age
• who have given informed consent
• with a diagnosis of a major depressive disorder according to the DSM-5 criteria
• in full hospitalization for less than 10 days in the care units of the Esquirol Hospital

You may not qualify if:

• Psychiatric comorbidity (personality disorder, addiction other than tobacco, eating disorder, bipolar disorder, obsessive-compulsive disorder, schizophrenia and related disorders)
• Proven sensory or neurological disability
• Inability to understand the questionnaires and information related to the study
• Hospitalization under constraint, pregnancy, subjects under guardianship or curatorship, lack of social protection

Sponsors & Collaborators

• Centre Hospitalier Esquirol: lead

Study Sites (1)

CH Esquirol

Limoges, 87000, France

Location

MeSH Terms

Conditions

Depressive Disorder, Major

Condition Hierarchy (Ancestors)

Depressive Disorder; Mood Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Psychomotor Therapist

Study Record Dates

• First Submitted: December 15, 2022
• First Posted: January 17, 2023
• Study Start: January 10, 2022
• Primary Completion: January 10, 2022
• Study Completion: January 10, 2024
• Last Updated: February 18, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)