Prevalence, Associated Factors Points and Implementation of Care Procedures of Chronic Obstructive Pulmonary Disease Exacerbation in Healthcare Institution

NCT05682404 | Completed

• 1 other identifier: OPEDEXA (38RC17.073)
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is a public health problem responsible for high mortality rate and significant costs for society. The disease evolution is punctuated by exacerbations worsening the health state of patients. Many guidelines of care procedures have been written but many disparities persist in medical practices. This pilot prospective observational study is an overview of current local practices in the university health center of Grenoble Alpes and it is the first step towards developing a regional observatory in order to standardize and improve patient cares. The primary outcome is to compare the international guidelines to the local practices regarding the prescription of key treatments of exacerbation, especially antibiotics.

Conditions

COPD Exacerbation

Keywords

COPD; exacerbation; Prospective; Observational; Professional practices guidelines

Outcome Measures

Primary Outcomes (1)

• Percentage of antibiotics prescriptions following the guidelines in COPD exacerbation.

  Adherence to guidelines regarding antibiotics prescription in COPD exacerbation that is justified by : * sputum purulence * severe symptoms * severe comorbidities * pneumonia

  up to 30 days

Secondary Outcomes (7)

• Percentage of corticosteroids prescriptions following the guidelines in COPD exacerbation.

  up to 30 days

• Percentage of hospitalization of patients following the guidelines in COPD exacerbation.

  up to 30 days

• Percentage of non invasive ventilation following the guidelines in COPD exacerbation.

  up to 30 days

• Percentage of invasive ventilation following the guidelines in COPD

  up to 30 days

• Percentage of minimal medical examinations following the guidelines in COPD exacerbation.

  up to 30 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Every Patient who is admitted for COPD exacerbation in emergency department or pneumology department or intensive care unit of university health center of Grenoble Alpes during the period of data collection.

You may qualify if:

• Patient older than 18 years (included)
• Known or suspected Chronic Obstructive Pulmonary Disease
• Admitted for COPD exacerbation in emergency department or pneumology department or intensive care unit of university health center of Grenoble Alpes during the period of data collection.

You may not qualify if:

• opposition to participate at the study
• Patients under the law

Sponsors & Collaborators

• University Hospital, Grenoble: lead

Study Sites (1)

CHU Grenoble Alpes

Grenoble, France

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 16, 2019
• First Posted: January 12, 2023
• Study Start: October 1, 2017
• Primary Completion: March 30, 2018
• Study Completion: June 30, 2018
• Last Updated: January 12, 2023

Record last verified: 2023-01

Locations

FR (1)