NCT05671939

Brief Summary

Although a number of clinical predictive models were developed to predict postoperative pulmonary complications, few predictive models have been used in elderly patients. In this study, the researchers aim to compare different algorithms to predict postoperative pulmonary complications in elderly patients and to assess the risk of postoperative pulmonary complications in elderly patients.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2023

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2023

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

January 2, 2023

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 5, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2023

Completed
Last Updated

January 5, 2023

Status Verified

December 1, 2022

Enrollment Period

Same day

First QC Date

January 2, 2023

Last Update Submit

January 3, 2023

Conditions

Postoperative Pulmonary Complications

Outcome Measures

Primary Outcomes (1)

  • Postoperative pulmonary complications

    within one week after surgery

Secondary Outcomes (1)

  • Postoperative pulmonary complications

    30 days after surgery

Study Arms (2)

Training set

The whole cohort is randomly assigned to a training cohort and validation cohort.

validation set

The whole cohort is randomly assigned to a training cohort and validation cohort.

Eligibility Criteria

Age65 Years+
Sexall
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

older patients received general anesthesia in Wuhan Union Hospital from January 1, 2014 to December 31, 2019.

You may qualify if:

  • Age 65 years or older
  • receiving invasive ventilation during general anesthesia for surgery

You may not qualify if:

  • preoperative mechanical ventilation
  • procedures related to a previous surgical complication
  • a second operation after surgery
  • organ transplantation
  • discharged within 24 hours after surgery
  • cardiac surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Qingping Wu, PhD

CONTACT

13971605283wqp1968@163.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 2, 2023

First Posted

January 5, 2023

Study Start

January 1, 2023

Primary Completion

January 1, 2023

Study Completion

March 1, 2023

Last Updated

January 5, 2023

Record last verified: 2022-12