NCT05669105

Brief Summary

The study objective is to collect biospecimen samples (e.g., whole blood) from participants diagnosed with active lung cancer to investigate the immune response to develop treatments and therapies.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 19, 2022

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

December 13, 2022

Completed
17 days until next milestone

First Posted

Study publicly available on registry

December 30, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2024

Completed
Last Updated

November 22, 2023

Status Verified

November 1, 2023

Enrollment Period

2.1 years

First QC Date

December 13, 2022

Last Update Submit

November 20, 2023

Conditions

Keywords

lung cancerNSCLC

Outcome Measures

Primary Outcomes (1)

  • Biospecimen & Clinical Data Collection

    The primary objective is to collect 2000 whole blood samples from subjects who are diagnosed with active lung cancer. The purpose of this study is to collect biospecimen samples (e.g., whole blood) from participants diagnosed with various active lung cancers so that investigations can analyze how the immune response can take place, and aid in understanding active lung cancer biomarkers for future early diagnosis and treatment options.

    10 years

Interventions

Specimen sampleDIAGNOSTIC_TEST

Participants will have up to 100 mL of whole blood collected.

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study will enroll up to 200 participants. Recruitment will occur through Sanguine advertisements, partnerships with cancer foundations, and cancer centers. Participants may be contacted for future studies.

You may qualify if:

  • Participants willing and able to provide written informed consent
  • Participants are willing and able to provide appropriate photo identification
  • Participant's age 18 - 100 years old
  • Participants diagnosed with active non-small cell lung cancer (Adenocarcinoma or Squamous Cell only. All stages are acceptable.)
  • Participants must have associated tissue biomarker data (EFGR and MET mutations) in their medical records

You may not qualify if:

  • Participants who are pregnant or nursing
  • Participants with a known history of HIV, hepatitis, or other infectious diseases
  • Participants who have taken an investigational product in the last 30 days
  • Participants who have experienced excess blood loss, including blood donation defined as 250 mL in the last month or 500 mL in the previous two months
  • Participants currently enrolled in a clinical trial
  • Participants currently in remission

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sanguine Biosciences

Waltham, Massachusetts, 02451, United States

RECRUITING

MeSH Terms

Conditions

Carcinoma, Non-Small-Cell LungLung Neoplasms

Condition Hierarchy (Ancestors)

Carcinoma, BronchogenicBronchial NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 13, 2022

First Posted

December 30, 2022

Study Start

February 19, 2022

Primary Completion

March 31, 2024

Study Completion

March 31, 2024

Last Updated

November 22, 2023

Record last verified: 2023-11

Locations