Key Insights

Highlights

Success Rate

72% trial completion

Published Results

136 trials with published results (13%)

Research Maturity

329 completed trials (33% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.6%

127 terminated out of 1010 trials

Success Rate

72.1%

-14.4% vs benchmark

Late-Stage Pipeline

8%

81 trials in Phase 3/4

Results Transparency

41%

136 of 329 completed with results

Key Signals

136 with results72% success127 terminated

Data Visualizations

Phase Distribution

804Total
Not Applicable (115)
Early P 1 (12)
P 1 (267)
P 2 (329)
P 3 (69)
P 4 (12)

Trial Status

Completed329
Recruiting192
Unknown174
Terminated127
Active Not Recruiting88
Not Yet Recruiting50

Trial Success Rate

72.1%

Benchmark: 86.5%

Based on 329 completed trials

Clinical Trials (1010)

Showing 20 of 20 trials
NCT06694454Phase 1Recruiting

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT06789172Phase 1Recruiting

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

NCT04928846Phase 3RecruitingPrimary

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT05076760Phase 1Recruiting

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

NCT04984811Phase 2Terminated

NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC

NCT07218003Phase 1Enrolling By InvitationPrimary

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

NCT03340506Phase 4Recruiting

Dabrafenib and/or Trametinib Rollover Study

NCT04262856Phase 2CompletedPrimary

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

NCT07462377Phase 1Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

NCT03306992Phase 3CompletedPrimary

Precision-exercise-prescription for Lung Cancer Patients Undergoing Surgery: The PEP Study

NCT05254782RecruitingPrimary

Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection

NCT04791839Phase 2Active Not RecruitingPrimary

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

NCT05789069Phase 1Active Not Recruiting

A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

NCT07630077Phase 2Not Yet RecruitingPrimary

Trastuzumab Rezetecan(SHR-A1811) Combined With Ivonescimab (AK112) in Locally Advanced or Metastatic Non-small Cell Lung Cancer Harboring HER2 Gene Abnormalities

NCT07234877Phase 2Not Yet RecruitingPrimary

Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets

NCT07269782Phase 2RecruitingPrimary

A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC

NCT04566393Unknown

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

NCT05062980Phase 1TerminatedPrimary

Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer

NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

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