Key Insights

Highlights

Success Rate

72% trial completion

Published Results

138 trials with published results (14%)

Research Maturity

334 completed trials (33% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.7%

129 terminated out of 1015 trials

Success Rate

72.1%

-14.4% vs benchmark

Late-Stage Pipeline

8%

81 trials in Phase 3/4

Results Transparency

41%

138 of 334 completed with results

Key Signals

138 with results72% success129 terminated

Data Visualizations

Phase Distribution

809Total
Not Applicable (116)
Early P 1 (12)
P 1 (269)
P 2 (331)
P 3 (69)
P 4 (12)

Trial Status

Completed334
Recruiting188
Unknown170
Terminated129
Active Not Recruiting93
Not Yet Recruiting51

Trial Success Rate

72.1%

Benchmark: 86.5%

Based on 334 completed trials

Clinical Trials (1015)

Showing 20 of 20 trials
NCT06694454Phase 1Recruiting

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

NCT06540196Not ApplicableRecruiting

The Development, Safety, and Feasibility of an Artificial Intelligence-Powered Platform (NodeAI) for Real-Time Prediction of Mediastinal Lymph Node Malignancy During Endobronchial Ultrasound Staging for Lung Cancer

NCT04736173Phase 2Active Not RecruitingPrimary

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

NCT04928846Phase 3RecruitingPrimary

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT03141359Phase 2Active Not Recruiting

Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC

NCT06150664Phase 1RecruitingPrimary

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

NCT05616624Phase 1TerminatedPrimary

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

NCT03915678Phase 2Active Not Recruiting

Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors

NCT04258137Not ApplicableActive Not Recruiting

Circulating DNA to Improve Outcome of Oncology PatiEnt. A Randomized Study

NCT05714553Phase 1Terminated

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

NCT03917043Phase 1Recruiting

APG-2449 in Patients With Advanced Solid Tumors

NCT06902272Phase 2RecruitingPrimary

ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

NCT05317858Phase 3Recruiting

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

NCT06033248RecruitingPrimary

Using Urine Samples to Identify Lung Cancer

NCT07253142Phase 2RecruitingPrimary

A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer

NCT05098132Phase 1Recruiting

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

NCT07718243Phase 1Not Yet Recruiting

Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLC

NCT06312137Phase 3RecruitingPrimary

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT06814496Phase 1Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

NCT07306624Phase 2RecruitingPrimary

Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer

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