Weight Loss and Aggression

NCT05654584 | Unknown DMC

• 1 other identifier: ANILERGİNNN
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Obesity has become an important medical and social problem in western countries today. Although many surgical procedures are performed for obesity, Laparoscopic sleeve gastrectomy (LSG) has become the most common bariatric procedure in obesity. The absence of digestive anastomosis, the absence of mesenteric defects that may cause internal hernias and foreign materials such as gastric band are among the advantages of this surgical method. Obesity is a complex multifactorial disease. Obesity is not a mental disorder, but is associated with serious serious conditions and increases the risk of mental disorders. The social label of obesity will have long-lasting devastating effects on mental health. In addition, obesity is associated with undesirable conditions; Misperception of dietary needs, self-perceived health status and potential social isolation, negative attitude towards appearance, aggression, depression, anxiety, attention deficit/hyperactivity disorder, behavioral problem, and bullying are some of the problems associated with obesity. Body changes are important in the experience of being different from their peers and can result in lowered self-esteem and be a barrier to social functioning. Studies on this condition have shown that obese subjects have poor social functioning and social skills. There are many factors that cause aggression, but obesity is one of them. Although there are many studies examining the relationship between overweight and aggression in children and adolescent patient groups, studies examining the adult patient group are limited. Starting from this point, we aimed to determine the change in aggression after weight loss in patients who underwent LSG surgery in the study we created.

Conditions

Obesity; Obesity, Morbid; Aggression

Keywords

agression; obesity; laparoscopic sleeve gastrectomy; morbid obesity

Outcome Measures

Primary Outcomes (1)

• agression score after weight loss

  After significant weight loss in the first year after laparoscopic sleeve gastrectomy, the preoperative aggression questionnaires will be re-administered to all patients.

  1 year

Secondary Outcomes (1)

• agression score before weight loss

  1 year

Study Arms (2)

agression before surgery

The group that the aggression assessment when morbidly obese before surgery

Procedure: laparoscopic sleeve gastrectomy

agression after surgery

group reassessed for aggression following postoperative weight loss

Procedure: laparoscopic sleeve gastrectomy

Interventions

laparoscopic sleeve gastrectomy PROCEDURE

Laparoscopic sleeve gastrectomy surgery will be performed by a single surgeon.

agression after surgery; agression before surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients undergoing laparoscopic sleeve gastrectomy were included in the study. It was planned to investigate the changes in aggression rates before and after weight loss by applying aggression questionnaires to all patients.

You may qualify if:

• years and older and younger than 64 years old.
• At least 5 years of morbid obesity (BMI \>40 or \>35 comorbidity)
• Patients with temporary or inadequate response (less than 10% of body weight will be considered insufficient) weight loss despite diet for at least 6 months before the operation under the guidance of a dietitian.

You may not qualify if:

• Past upper gastrointestinal surgery,
• Paraesophageal (type 2), mixed (type 3), or sliding hiatal hernias of 3 cm or more,
• Patients with esophagitis and/or Barrett's metaplasia in upper gastrointestinal system (GIS) endoscopy
• Those with peripheral vascular disease Those with a history of cerebrovascular accident
• Patients with coagulopathy
• History of chronic analgesic use
• Patients with perioperative complications
• Patients with a previous psychiatric diagnosis other than depression
• Patients who lost less than 10% of their initial weight at the 6th month after the operation
• patients with chronic alcohol use
• patients with recent psychological trauma
• low-income patients

Sponsors & Collaborators

• Fatih Sultan Mehmet Training and Research Hospital: lead

Study Sites (1)

Fatih Sultan Mehmet Research and Training Hospital

Istanbul, 34734, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Obesity; Obesity, Morbid; Aggression

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Aberrant Motor Behavior in Dementia; Behavioral Symptoms; Behavior; Social Behavior

Central Study Contacts

ANIL ERGİN

CONTACT

+905342245364; dranilergin@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Uzman Doktor

Study Record Dates

• First Submitted: December 8, 2022
• First Posted: December 16, 2022
• Study Start: December 15, 2022
• Primary Completion: December 15, 2023
• Study Completion: February 15, 2024
• Last Updated: December 16, 2022

Record last verified: 2022-12

Locations

TU (1)