NCT05648292|UnknownDMC
The Relationships Between Personal Identity, Autobiographical Memory and Future Thinking in People With Multiple Sclerosis
SELFSEP
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SELFSEP
Sponsor study identifier
observational
90
1 country
1
Study Start
December 7, 2022
Actual (reported)Primary Completion
December 7, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 7, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future (i.e., future thinking) . While our previous work has shown that people with relapsing-remitting multiple sclerosis (pwRRMS) have autobiographical memory and future thought disorders, their impact on personal identity has not yet been explored. Based on a cognitive and clinical neuropsychology approach, this research project aims to better understand the cognitive mechanisms involved in the relationship between identity, autobiographical memory and future thinking in pwRRMS. We will examine the extent to which pwRRMS manage to maintain and reshape their identity through life experiences, with a particular interest in the potential integration of the disease as a facet of their identity. In addition, we will explore the positive and/or negative consequences of disease-related identity changes on emotional well-being and quality of life, as well as their links with the duration and severity of the disease. Overall, this research project will contribute to identify new therapeutic levers that can be used for the development of adapted and personalized care.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 7, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 5, 2022
Actual (reported)December 7, 2022
Actual (reported)December 13, 2022
Actual (reported)December 7, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
June 7, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Relationships between personal identity, autobiographical memory and future thinking
Scores obtained at the I AM and I WILL BE tasks assessing the access, qualitative properties of self-concepts, episodic richness and temporal organization of past and future events around self-concepts (between-group comparisons, pwRRMS versus control group)
15 days
Relationships between personal identity, psychological functioning and clinical characteristics
15 days
45 individuals with relapsing-remitting multiple sclerosis
45 individuals with no chronic disease, matched in age, gender and level of education
* The clinical group will complete: * the BCcogSEP: a comprehensive neuropsychological examination * the IAM and I WILL BE tasks; experimental neuropsychological tasks to assess autobiographical memory, future thinking and personal identity * A series of questionnaires including the BRIEF COPE, the Connor Davidson Resilience Scale, the Satisfaction with Life Scale and the Hospital Anxiety and Depression Scale, which respectively assess coping strategies, resilience, life satisfaction and anxiety/depression * The control group will complete: * the IAM and I WILL BE tasks; experimental neuropsychological tasks to assess autobiographical memory, future thinking and personal identity * A series of questionnaires including the BRIEF COPE, the Connor Davidson Resilience Scale, the Satisfaction with Life Scale and the Hospital Anxiety and Depression Scale, which respectively assess coping strategies, resilience, life satisfaction and anxiety/depression
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Primary care clinic
Hopital Raymond Poincaré Garches
Garches, Hauts De Seine, 92380, France
Alexandra ERNST, PhD
Laboratoire DysCo - Université Paris 8
First Submitted
December 5, 2022
First Posted
December 13, 2022
Study Start
December 7, 2022
Actual (reported)Primary Completion
December 7, 2024
Estimated (date passed)Contact the study team to confirm eligibility.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 7, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
September 6, 2023
Record last verified: 2023-09
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