Key Insights

Highlights

Success Rate

86% trial completion

Published Results

41 trials with published results (18%)

Research Maturity

133 completed trials (59% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

9.7%

22 terminated out of 227 trials

Success Rate

85.8%

-0.7% vs benchmark

Late-Stage Pipeline

26%

59 trials in Phase 3/4

Results Transparency

31%

41 of 133 completed with results

Key Signals

41 with results86% success22 terminated

Data Visualizations

Phase Distribution

166Total
Not Applicable (50)
Early P 1 (2)
P 1 (26)
P 2 (29)
P 3 (35)
P 4 (24)

Trial Status

Completed133
Unknown27
Recruiting24
Terminated22
Active Not Recruiting12
Withdrawn5

Trial Success Rate

85.8%

Benchmark: 86.5%

Based on 133 completed trials

Clinical Trials (227)

Showing 20 of 20 trials
NCT06408259Phase 3RecruitingPrimary

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

NCT06345157Active Not RecruitingPrimary

ITAKOS - Italian Observation, Multicenter, Prospective Study of Ofatumumab in RRMS Patients

NCT04625153Phase 2TerminatedPrimary

RC18 in Patients With Relapsing Remitting Multiple Sclerosis:a Phase II Trial

NCT05168384Phase 1Active Not Recruiting

Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis

NCT06495593Phase 4Enrolling By InvitationPrimary

Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis

NCT05359653Phase 1Recruiting

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

NCT05201638Phase 3Active Not RecruitingPrimary

Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

NCT06390930Not ApplicableRecruiting

Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

NCT06413602Not ApplicableActive Not Recruiting

The Synergistic Effects of AIH and FES in Persons With MS

NCT06569550Not ApplicableRecruitingPrimary

Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis

NCT07280871Not Yet RecruitingPrimary

Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis: A Trans-regional Digital Health Effort Unlocking the Potential of Artificial Intelligence and Data Science in Health Care

NCT04220814Not ApplicableCompletedPrimary

Evaluation of the Impact of Lesions of the Motor and Proprioceptive Brain and Pan-medullary Pathways on Their Clinically and Electrophysiologically Assessed Function in Multiple Sclerosis

NCT06526364Recruiting

Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)

NCT04768777Not ApplicableNot Yet RecruitingPrimary

Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis

NCT05265728Phase 3TerminatedPrimary

A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple Sclerosis

NCT03500328Not ApplicableActive Not RecruitingPrimary

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

NCT05658601CompletedPrimary

A Study to Describe the Switching From a First- or Second-line Disease Modifying Therapy (DMT) to Ozanimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)

NCT05964829Not ApplicableRecruiting

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

NCT02040298Phase 2CompletedPrimary

Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis

NCT05007483Not ApplicableActive Not RecruitingPrimary

Efficacy of Diet on Quality of Life in Multiple Sclerosis

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