NCT05646342

Brief Summary

fluid resuscitation is one of the bases of strategies in ICU to take in charge patients , one of the technique to evaluate preload charge , is Passive leg raising, that allows reliable prediction of fluid responsiveness even in patients with spontaneous breathing activity or arrhythmias . In recent years, hemodynamic response to passive leg raising (PLR) has been popularized as a dynamic test of preload responsiveness \[1\]. This manoeuvre provides an "auto-fluid challenge" which is rapid, transient and reversible. PLR transfers blood contained in the venous reservoir of the lower extremities to the central venous compartment leading to a transient increase in preload and an increase in cardiac output by Frank-Starling mechanism in preload responsive individuals. untille now the usseuful of PLR in Pregnancy, and also The validity of dynamic measurements of preload to predict fluid response during pregnancy are note clear in littérature .

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 5, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 12, 2022

Completed
20 days until next milestone

Study Start

First participant enrolled

January 1, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2023

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2023

Completed
Last Updated

December 12, 2022

Status Verified

December 1, 2022

Enrollment Period

3 months

First QC Date

December 5, 2022

Last Update Submit

December 5, 2022

Conditions

Keywords

COPLRETTPregnanacy

Outcome Measures

Primary Outcomes (1)

  • PLR in a good helath after 24 week of preganancy

    we will realise ETT before and after PLR in all women that eligible of crieria inclusion , in obstetric consultation

    in all the 5 mounths

Interventions

we will realise ETT before and after PLR in all women that eligible of crieria inclusion , in obstetric consultation

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Moroccan population

You may qualify if:

  • All Pregnante Women in good health after 24 week of preganancy

You may not qualify if:

  • All young women under 18 years old
  • unhealthy women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Cardiac Output, High

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

December 5, 2022

First Posted

December 12, 2022

Study Start

January 1, 2023

Primary Completion

March 30, 2023

Study Completion

April 1, 2023

Last Updated

December 12, 2022

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share