The Initiating Factors of Myopia Among Primary and Secondary School Students in Tianjin

NCT05637827 | Unknown

• 1 other identifier: Tianjin children myopia
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

There was a prospective cohort observational study. Forty hyperopic children, 40 myopic children and 120 emmetropia children were randomly selected from grade 1 to grade 3, and were followed up every six months for 3 years. All patients received cycloplegic refraction examination, ocular biological test, binocular visual function test and a questionnaire related to daily eye habits. A multi-level and multi-dimensional data analysis model was constructed to explore the possible factors affecting the occurrence and development of myopia in children.

Conditions

Myopia; Refractive Error

Outcome Measures

Primary Outcomes (2)

• The changes of refractive error

  The changes of refractive error between visit time in every 6 months

  Every 6 months for a period 3 years

• The changes of axial length

  The changes of axial length between visit time in every 6 months.

  Every 6 months for a period 3 years

Study Arms (3)

children with hyperopia

The refractive error and axial length of eye were observed

Other: No intervention

children with emmetropia

The refractive error and axial length of eye were observed

Other: No intervention

children with myopia

The refractive error and axial length of eye were observed

Other: No intervention

Interventions

No intervention OTHER

There was no intervention in each group, and only the natural development was observed

children with emmetropia; children with hyperopia; children with myopia

Eligibility Criteria

• Age: 5 Years - 11 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Healthy children with hyperopia, emmetropia and myopia

You may qualify if:

• students in grades 1-3
• Can cooperate with the examination of students

You may not qualify if:

• Obvious strabismus and amblyopia
• Eye diseases that affect vision, such as congenital cataracts, glaucoma, and retinal diseases
• History of ocular surgery

Sponsors & Collaborators

• Tianjin Eye Hospital: lead

Study Sites (1)

Tianjin Eye Hospital

Tianjin, Tianjin Municipality, 300020, China

RECRUITING

Related Publications (3)

• Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, Wong TY, Naduvilath TJ, Resnikoff S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology. 2016 May;123(5):1036-42. doi: 10.1016/j.ophtha.2016.01.006. Epub 2016 Feb 11.

  PMID: 26875007 RESULT

• Rose KA, French AN, Morgan IG. Environmental Factors and Myopia: Paradoxes and Prospects for Prevention. Asia Pac J Ophthalmol (Phila). 2016 Nov/Dec;5(6):403-410. doi: 10.1097/APO.0000000000000233.

  PMID: 27898443 RESULT

• Seidemann A, Schaeffel F. An evaluation of the lag of accommodation using photorefraction. Vision Res. 2003 Feb;43(4):419-30. doi: 10.1016/s0042-6989(02)00571-0.

  PMID: 12535999 RESULT

MeSH Terms

Conditions

Myopia; Refractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Central Study Contacts

yan wang

CONTACT

+86-22-27305083; wangyan7143@vip.sina.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 26, 2022
• First Posted: December 5, 2022
• Study Start: November 1, 2021
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: December 5, 2022

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)