NCT05632978

Brief Summary

The goal of this observational study is to learn more about phenotypic, genetic, biochemical, neurophysiological and radiological patterns in epilepsy. Participants will be asked to consent to use of clinical and paraclinical data (obtained during standard care) for research, and will be asked to donate blood samples at their routine clinic visits.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,000

participants targeted

Target at P75+ for all trials

Timeline
80mo left

Started Apr 2023

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress32%
Apr 2023Dec 2032

First Submitted

Initial submission to the registry

November 21, 2022

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 1, 2022

Completed
5 months until next milestone

Study Start

First participant enrolled

April 24, 2023

Completed
9.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2032

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2032

Last Updated

February 13, 2025

Status Verified

February 1, 2025

Enrollment Period

9.6 years

First QC Date

November 21, 2022

Last Update Submit

February 11, 2025

Conditions

Epilepsy

Outcome Measures

Primary Outcomes (1)

  • Establish population-based cohort of people with epilepsy

    Establish a population-based cohort of people with epilepsy and associated real-world clinical, paraclinical and biological data.

    10-years

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All people over 16 years old being investigated or followed-up for epilepsy.

You may qualify if:

  • Individual is being investigated for epilepsy and under the clinical care of the epilepsy unit at Cardiff \& Vale University Health Board or regional clinics in Cwm Taf.
  • Individual is at least 16 years old.
  • Informed consent sought and given by individual.

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cardiff and Vale UHB

Cardiff, United Kingdom

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Plasma, serum, DNA.

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Khalid Hamandi

    Cardiff & Vale University Health Board

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Khalid Hamandi

CONTACT

+44(0)2921843454khalid.hamandi@wales.nhs.uk

Rachel Norman

CONTACT

+44(0)2921846126rachel.norman2@wales.nhs.uk

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 21, 2022

First Posted

December 1, 2022

Study Start

April 24, 2023

Primary Completion (Estimated)

December 1, 2032

Study Completion (Estimated)

December 1, 2032

Last Updated

February 13, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations

GB(1)