NCT05629650

Brief Summary

The goal of this clinical trial is to determine the feasibility of a 12-week program of Tai Chi for memory (TCM) among older adults with mild cognitive impairment (MCI) or dementia and to determine the effects of TCM on physical functioning, depression, and health-related QoL. Two experimental groups will be recruited for inclusion criteria of community-residing older adults with a diagnosis of either MCI or Dementia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
41

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 28, 2019

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 10, 2022

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

November 12, 2022

Completed
17 days until next milestone

First Posted

Study publicly available on registry

November 29, 2022

Completed
Last Updated

December 1, 2022

Status Verified

November 1, 2022

Enrollment Period

7 months

First QC Date

November 12, 2022

Last Update Submit

November 29, 2022

Conditions

Cognitive Impairment

Keywords

Tai Chicognitive impairmentdementia

Outcome Measures

Primary Outcomes (4)

  • physical function-grip strength

    grip strength by assessed in both hands using a digital hand dynamometer (0-90 kg; Labisen KS-301)

    changes from pretest to 12 week posttest scores

  • physical function - flexibility

    by the standard sit-and-reach test (SSRT)

    changes from pretest to 12 week posttest scores

  • physical function - balance

    assessed using a one-leg-standing balance test (OLST)

    changes from pretest to 12 week posttest scores

  • physical function - mobility

    assessed by the Timed Up and Go test (TUG)

    changes from pretest to 12 week posttest scores

Secondary Outcomes (2)

  • emotional functioning - depression

    changes from pretest to 12 week posttest scores

  • Short Form Health Survey 12 (SF12)

    changes from pretest to 12 week posttest scores

Study Arms (1)

Tai Chi for memory

EXPERIMENTAL

TCM is a standardized type of Tai Chi for health developed by Dr. Lam specifically for those who experience or want to prevent cognitive problems. TCM, consisting of 12 Sun-style and Yang-style Tai Chi movements, can be provided while sitting and while standing with five blocked movement sets so that cognitively impaired individuals (MCI vs. dementia) are able to follow them.

Behavioral: Tai Chi for memory

Interventions

Tai Chi for memoryBEHAVIORAL

The adapted form of TCM will be provided at 60 minutes per session, twice a week for 12 weeks by a certified Tai Chi instructor who had experience in teaching older adults with cognitive impairments.

Tai Chi for memory

Eligibility Criteria

Age75 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • community-residing older adults aged 75 years or older,
  • registered at the public dementia prevention centers for dementia screening by health professionals with the diagnosis of either MCI or dementia,
  • Korean version of the Montreal Cognitive Assessment (MoCA-K) score of 22 or lower,
  • agreed to participate in the Tai Chi program twice a week for 12 weeks.

You may not qualify if:

  • participated in any formal regular exercise program during the previous 6 months, and

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tai Chi for health institute

Daejeon, 35010, South Korea

Location

Related Publications (1)

  • Oh H, Song R, Kim SJ. Effects of 12-week Tai Chi program on physical function, depression, and quality of life among cognitively impaired older adults: a feasibility study. BMC Geriatr. 2023 Mar 3;23(1):118. doi: 10.1186/s12877-023-03840-2.

    PMID: 36869290DERIVED

MeSH Terms

Conditions

Cognitive DysfunctionDementia

Interventions

Tai Ji

Condition Hierarchy (Ancestors)

Cognition DisordersNeurocognitive DisordersMental DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsExercise Movement TechniquesPhysical Therapy Modalities

Study Officials

  • Rhayun Song, PhD

    Chungnam National University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Model Details: two intervention groups (1) those with MCI (2) those with dementia
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 12, 2022

First Posted

November 29, 2022

Study Start

July 1, 2018

Primary Completion

January 28, 2019

Study Completion

January 10, 2022

Last Updated

December 1, 2022

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will share

upon request, study protocol and the data without individual IDs can be shared with other researchers.

Shared Documents
STUDY PROTOCOL, CSR
Time Frame
January-December, 2024
Access Criteria
researchers or reviewers who requested for clinical study or meta-analysis

Locations

KR(1)