NCT05626933

Brief Summary

Nasopharyngoscopic examination of the 20 patients with secondary VPI following 2 flap palatoplasty will be done for visualization of the velopharyngeal port, allowing assessment of the pattern and grade of velopharyngeal closure during speech and the presence or absence of a velopharyngeal gap and after VPI repair by Buccinator myomucosal flap with Furlow palatoplasty

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 11, 2022

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

November 15, 2022

Completed
10 days until next milestone

First Posted

Study publicly available on registry

November 25, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2022

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 2, 2023

Completed
Last Updated

November 25, 2022

Status Verified

November 1, 2022

Enrollment Period

2 months

First QC Date

November 15, 2022

Last Update Submit

November 23, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • grade of velopharyngeal closure during speech

    Nasopharyngoscopic examination of the patients with secondary velopharyngeal insufficiency ( VPI) following two flap palatoplasty cleft palate repairs will be done for assessment of velopharyngeal closure grade during speech after VPI repair by Buccinator myomucosal flap with Furlow palatoplasty

    immediate postoperative

Study Arms (1)

Buccinator myomucosal flap with Furlow palatoplasty

EXPERIMENTAL
Procedure: Buccinator myomucosal flap with Furlow palatoplasty

Interventions

Anatomical restoration concept using Buccinator myomucosal flap with Furlow palatoplasty is an effective technique for lengthening the palate and improving speech outcomes

Buccinator myomucosal flap with Furlow palatoplasty

Eligibility Criteria

Age5 Years - 6 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • years old children with previous treated complete cleft palate with 2 flap palatoplasty technique, nonsyndromic.
  • lip and palate repair performed by one craniofacial surgeon

You may not qualify if:

  • Patients with syndromic cleft lip.
  • Bilateral cleft lip
  • Patient older younger 5 years.
  • Associated Cardiac anomalies.
  • Any systemic condition

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fayoum University

Al Fayyum, Egypt

RECRUITING

Related Publications (1)

  • Aboulhassan MA, Elrouby IM, Refahee SM, Abd-El-Ghafour M. Effectiveness of secondary furlow palatoplasty with buccal myomucosal flap in correction of velopharyngeal insufficiency in patients with cleft palate. Clin Oral Investig. 2024 Apr 17;28(5):257. doi: 10.1007/s00784-024-05607-4.

MeSH Terms

Conditions

Velopharyngeal Insufficiency

Condition Hierarchy (Ancestors)

Mouth AbnormalitiesMouth DiseasesStomatognathic DiseasesPharyngeal DiseasesStomatognathic System AbnormalitiesOtorhinolaryngologic DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

shaimaa refahee, phd

CONTACT

mamdouh aboelhassan, phd

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

November 15, 2022

First Posted

November 25, 2022

Study Start

November 11, 2022

Primary Completion

December 30, 2022

Study Completion

January 2, 2023

Last Updated

November 25, 2022

Record last verified: 2022-11

Locations