A Study of Border Line Cases of Velopharyngeal Incompetence Using Cephalometry and Nasofibroscopy

NCT03259061 | Unknown

• 1 other identifier: Border line VPI study
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this work is to evaluate the role of cephalometry \&nasofibroscopy as objective tools in order to confirm the diagnosis based upon the clinical judgment of border line cases suspected to have velopharyngeal incompetence or insufficiency.

Conditions

Velopharyngeal Insufficiency

Outcome Measures

Primary Outcomes (1)

• Comparison between Cephalometric and nasofibroscopic findings and clinical findings

  Assessment of the function of velopharyngeal valve by nasofibroscopy and cephalometric measurements in clinically border line cases of velopharyngeal incompetence in order to ensure the presence of Velophayngeal incompetence

  Baseline

Interventions

Flexible fiberoptic nasopharyngoscopy DEVICE

1. Flexible fiberoptic nasopharyngoscopy (FFN) allows direct transnasal observation of the anatomy and dynamic activity of the velopharyngeal sphincter. Such observations can be recorded for permanent documentation by coupling FFN to a video camera with simultaneous audio recording. Numerous published reports discuss the advantages of FFN as a clinical method for evaluating velopharyngeal function during speech (10). 2. Cephalometric analysis, is the clinical application of cephalometry. It is analysis of the dental and skeletal relationships of a human skull and is frequently used by dentists, orthodontists, and oral and maxillofacial surgeons as a treatment planning tool. Cephalometric analysis can also be applied for assessing the velopharyngeal structure and function. More specifically, velopharyngeal function in terms of its shape and mobility was analyzed quantitatively on the basis of cephalometric principle

Also known as: Cephalometry

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Any

You may qualify if:

• Patients must have border line velopharyngeal abnormality which was diagnosed clinically.
• Ability to understand and the willingness to sign a written informed consent(if he was a child so his parents or his guardian should has tis ability)

You may not qualify if:

• Mental Retardation.
• Presence of Neurological deficit affecting speech.
• Palatal paralysis or paresis.
• Overt cleft palate.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (11)

• Camargo LO, Rodrigues CM, Avelar JA. Oclusão velofaríngea em indivíduos submetidos à nasoendoscopia na Clínica de Educação para Saúde (CEPS) 20(1):35-48, 2001.

  BACKGROUND

• Skolnick ML, McCALL GN, Barnes M. The sphincteric mechanism of velopharyngeal closure. Cleft Palate J. 1973 Jul;10:286-305. No abstract available.

  PMID: 4513919 BACKGROUND

• Penido FA, Noronha RM, Caetano KI, Jesus MS, Di Ninno CQ, Britto AT. Correlação entre os achados do teste de emissão de ar nasal e da nasofaringoscopia em pacientes com fissura labiopalatina operada. Rev Soc Bras Fonoaudiol. 2007;12(2):126-34.

  BACKGROUND

• Mourão D, Souza GS, Torres LV, Vaz RN, Prado SG. Estudo sobre desenvolvimento fonológico em fissurados: implicações na fala e na linguagem. Estudos. 2006;33(5/6):425-41.

  BACKGROUND

• De Bodt M, Van Lierde K. Cleft palate speech and velopharyngeal dysfunction: the approach of the speech therapist. B-ENT. 2006;2 Suppl 4:63-70.

  PMID: 17366850 BACKGROUND

• Trindade IE, Genaro KF, Yamashita RP, Miguel HC, Fukushiro AP. [Proposal for velopharyngeal function rating in a speech perceptual assessment]. Pro Fono. 2005 May-Aug;17(2):259-62. doi: 10.1590/s0104-56872005000200015. Portuguese.

  PMID: 16909536 BACKGROUND

• Witt PD. Management of velopharyngeal dysfunction. In: Persing JA, Evans GR. Soft-tissue surgery of the craniofacial region. New York: Informa; 2007. p.113-28.

  BACKGROUND

• Smith BE, Kuehn DP. Speech evaluation of velopharyngeal dysfunction. J Craniofac Surg. 2007 Mar;18(2):251-61; quiz 266-7. doi: 10.1097/SCS.0b013e31803ecf3b.

  PMID: 17414269 BACKGROUND

• D'Antonio LL, Marsh JL, Province MA, Muntz HR, Phillips CJ. Reliability of flexible fiberoptic nasopharyngoscopy for evaluation of velopharyngeal function in a clinical population. Cleft Palate J. 1989 Jul;26(3):217-25; discussion 225.

  PMID: 2758674 BACKGROUND

• Mourino AP, Weinberg B. A cephalometric study of velar stretch in 8 and 10-year old children. Cleft Palate J. 1975 Oct;12:417-35.

  PMID: 1058753 BACKGROUND

• Simpson RK, Colton J. A cephalometric study of velar stretch in adolescent subjects. Cleft Palate J. 1980 Jan;17(1):40-7.

  PMID: 6928116 BACKGROUND

MeSH Terms

Conditions

Velopharyngeal Insufficiency

Interventions

Cephalometry

Condition Hierarchy (Ancestors)

Mouth Abnormalities; Mouth Diseases; Stomatognathic Diseases; Pharyngeal Diseases; Stomatognathic System Abnormalities; Otorhinolaryngologic Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Anthropometry; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques; Biometry; Epidemiologic Measurements; Public Health; Environment and Public Health

Central Study Contacts

Abdelazez Darwesh, doctor

CONTACT

+201002600619; dr.abdelazez.darwesh@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: August 19, 2017
• First Posted: August 23, 2017
• Study Start: September 1, 2017
• Primary Completion: September 1, 2019
• Study Completion: November 1, 2019
• Last Updated: August 23, 2017

Record last verified: 2017-08