NCT05625009

Brief Summary

Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section. Recently, Erector Spinae Plane Block (ESPB) has been defined and used in several clinical scenarios. However, data regarding the ESPB use in the aforementioned patient group is limited.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
94

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 11, 2022

Completed
11 days until next milestone

First Posted

Study publicly available on registry

November 22, 2022

Completed
2 days until next milestone

Study Start

First participant enrolled

November 24, 2022

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 24, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 2, 2023

Completed
Last Updated

May 6, 2023

Status Verified

May 1, 2023

Enrollment Period

2 months

First QC Date

November 11, 2022

Last Update Submit

May 3, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percentage of patients needed for rescue analgesic agent (diclofenac)

    24 hours

Secondary Outcomes (3)

  • Percentage of patients needed for rescue analgesic agent (opioid)

    24 hours

  • the dose of the opioid used

    24 hours

  • Percentage of patients experienced chronic pain

    2 months

Study Arms (2)

Experimental: Transversus Abdominis Plane Block (TAPB)

EXPERIMENTAL

patients received TAPB postoperatively

Procedure: Procedure/Surgery: Transversus Abdominis Plane Block (TAPB)

Experimental: Erector Spinae Plane Block (ESPB)

EXPERIMENTAL

patients received ESPB postoperatively

Procedure: Procedure/Surgery: Erector Spinae Plane Block (ESPB)

Interventions

Patients received TAPB postoperatively

Experimental: Transversus Abdominis Plane Block (TAPB)

Patients received ESPB postoperatively

Experimental: Erector Spinae Plane Block (ESPB)

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailscesarean section
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years
  • ASA2
  • Undergoing cesarean section under spinal anesthesia

You may not qualify if:

  • History of chronic pain
  • Body mass index \> 35
  • Urgent/emergent surgeries
  • Major bleeding
  • Any additional surgical procedure
  • Contraindication for any drugs used in the protocol
  • The presence of any instrumentation in the procedure sites

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Basaksehir Cam and Sakura City Hospital

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
The investigators who assessed pain scores postoperatively are blinded to the study groups Care providers on the yard are blinded to the study groups Outcome assessors are blinded to the study groups
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 11, 2022

First Posted

November 22, 2022

Study Start

November 24, 2022

Primary Completion

January 24, 2023

Study Completion

April 2, 2023

Last Updated

May 6, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will share

Locations