Acute Rehabilitation in Patients With COVID-19 Pneumonia

NCT05619666 | Unknown DMC

• 1 other identifier: 02/269-1
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 2

Brief Summary

COVID-19 can have different clinical manifestations including myalgia, arthralgia, neurological, cardiac, psychological and other manifestations.These patients are at greater risk of developing consequences of prolonged bed rest. Therefore physical medicine and rehabilitation could have an important role in the multidisciplinary treatment of these issues. Early respiratory and neuromuscular rehabilitation is necessary to improve functional physical limitations, performance, muscle strength, endurance as well as cognitive and emotional domains. Some studies proposed that rehabilitation protocols in the inpatient setting include early mobilisation, strength and endurance training with the aim of reducing weakness and dependency. This Study aimed to detect the effects of rehabilitation in patients with Covid-19 who were admitted in temporary Covid hospital in Serbia. Furthermore, to emphasize the importance of functional assessment of the patients, in identifying their problems and selections of priorities in planning the best therapeutic protocol.

Conditions

COVID-19; Rehabilitation; Physical Medicine

Keywords

Acute rehabilitation; COVID-19 pneumonia

Outcome Measures

Primary Outcomes (6)

• functional outcome of activity of daily living

  Bartel index (BI)

  up to three weeks

• functional outcome of cardiovascular and respiratory system

  six minute walk test (6MWT)

  up to three weeks

• functional outcome for assesing dyspnea

  Borg scale for dyspnea,

  up to three weeks

• functional outcome of mobility

  "Time Up and Go" test (TUG)

  up to three weeks

• functional outcome of lower limbs strength

  "Sit To Stand" test (STS)

  up to three weeks

• functional outcome of static balance

  "One Leg Stance Test" (OLST)

  up to three weeks

Study Arms (1)

Severity of COVID-19 infection

OTHER

Based on the severity of Covid-19 infection patients were divided into 2 groups: First group (MMG) mild to moderate group and second group (SSG) stable severe group.

Procedure: Acute rehabilitation program

Interventions

Acute rehabilitation program PROCEDURE

Patients included in the study started the rehabilitation program when they were hemodynamic stable, when it was determined that it was safe for patients. Until discharge from the hospital, a re-evaluation of neuromuscular and respiratory function was performed.

Severity of COVID-19 infection

Eligibility Criteria

• Age: 18 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Positive pharyngeal or nasal swab for SARS CoV-2, 3) SP O2\> 94% on admission, 4) body temperature under 37.5 5) Clinical stability defined by ability to perform bedside active mobilization without a reduction of oxygen saturation (SpO2) below 92%;

You may not qualify if:

• \) SP o2 \< 94% on admission, 2) Moderate and severe heart failure (grade III and IV, NY heart Association), 3) Paresis or plegia as a result of CVI or neurodegenerative disease, 4) Impaired cognitive status.

Sponsors & Collaborators

• Institut za Rehabilitaciju Sokobanjska Beograd: lead

Study Sites (2)

Tamara Filipovic

Belgrade, 11000, Serbia

RECRUITING

Institute for Rehabilitation

Belgrade, Serbia

RECRUITING

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Teaching assistant

Study Record Dates

• First Submitted: November 14, 2022
• First Posted: November 17, 2022
• Study Start: September 1, 2021
• Primary Completion: December 1, 2022
• Study Completion: January 1, 2023
• Last Updated: November 17, 2022

Record last verified: 2022-11

Locations

SE (2)