Study of the Angle Lambda and Ocular Dominance

NCT05613517 | Completed

• 2 other identifiers: APHP2210232022-A01045-38
• Study Type: observational
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle lambda and the ocular dominance depth in healthy individuals without ophthalmologic disorder. Then, seconds goals were defined as the study of the relation between the value of the angle lambda and the fixation disparity quantified with the Rousseau test. Relation between ocular dominance measured with the Guillon's test and the Hole-in-car test will also studied.

Conditions

No Eye Disorder

Keywords

Angle lambda; Ocular dominance; Fixation disparity; Pupillary axis; Line of sight

Outcome Measures

Primary Outcomes (2)

• Value of the angle lambda

  Semi-automatic digital method of measurement by eye photograph.

  Day 0

• Ocular dominance depth

  Guillon's and Hole-In-Card tests.

  Day 0

Secondary Outcomes (5)

• Fixation disparity

  Day 0

• Ocular dominance measurements quantified by the Hole-in-the-card method

  Day 0

• Guillon test

  Day 0

• Semi-automatic method of measurement by ocular photography

  Day 0

• Method using corneal topography

  Day 0

Study Arms (1)

Healthy individual

Healthy individual without eye disorder.

Other: Eye examination

Interventions

Eye examination OTHER

* orthoptic assessment (visual acuity, refraction, stereopsis test, Cover-test, evaluation of the disparity of fixation and ocular dominance, measurement of the inter-pupillary distance * ocular biometry * corneal topography * monocular photographs in photopic condition

Healthy individual

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy individuals without visual disorders

You may qualify if:

• \- Informed major subject not opposing to their participation in the study

You may not qualify if:

• Subject with strabismus or organic ophthalmologic pathology
• Or presenting a visual acuity lower than 10/10th
• Or with a history of eye surgery

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead
• URC-CIC Paris Descartes Necker Cochin: collaborator

Study Sites (1)

Hôpital Necker-Enfants Malades

Paris, 75015, France

Location

Study Officials

• Maxence Rateaux, PhD

  Assistance Publique - Hôpitaux de Paris

  PRINCIPAL INVESTIGATOR

• Dominique Bremond-Gignac, MD, PhD

  Assistance Publique - Hôpitaux de Paris

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 4, 2022
• First Posted: November 14, 2022
• Study Start: November 25, 2022
• Primary Completion: February 28, 2024
• Study Completion: February 28, 2024
• Last Updated: September 12, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)