Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study

NCT05611489 | Unknown

• 1 other identifier: Laparoscopic appendectomy
• Study Type: interventional
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

laparoscopic versus open appendectomy prospective randomized control study.Both surgical methods are safe and well established in clinical practice but there has been a controversy about which surgical procedure is the most appropriate in this research we are going to demonstrate which operative procedure is more beneficial with less disadvantages.

Conditions

Appendicitis Acute

Keywords

Laparoscopic appendectomy

Outcome Measures

Primary Outcomes (1)

• Operative time

  Time needed for operation

  1 year

Study Arms (2)

Open appendectomy

OTHER

Appendectomy will be done through Mcberney incision.

Procedure: Open appendectomy

Conventional lap appendectomy

OTHER

Three ports will be inserted as follows: One 10/12 umbilical port, one 5mm suprapubic (or right suprapubic)port, one 5mm or 10/12mm port in left iliac fossa (or left suprapubic).

Procedure: Conventional Lap appendectomy

Interventions

Open appendectomy PROCEDURE

performed With the patient in supine position.incision made lateral to McBurney's point.layers of the abdomen is exposed. If the cecum can be visualized, it can be mobilized and used to identify the appendix. Once the appendix is identified, the mesoappendix should be dissected and the appendiceal vessels divided between clamps. The appendiceal vessels are then ligated with silk sutures. A silk purse-string suture can then be placed around the appendiceal base.A 15-blade knife is then used to excise the appendix proximal to the right angle clamp.The appendiceal stump mucosa can be obliterated using electrocautery. Then good haemostasis and layered closure is done.

Open appendectomy

Conventional Lap appendectomy PROCEDURE

Three ports will be inserted as follows: One 10/12 umbilical port, one 5mm suprapubic (or right suprapubic)port, one 5mm or 10/12mm port in left iliac fossa (or left suprapubic). One additional trocar can be inserted following surgeons preference. Retraction of the appendix would be performed with a forceps. The mesoappendix will be divided with bipolar or monopolar cautery. The appendix stump will be ligated with suture loop or with an endo-stapler. The specimen will be delivered within a plastic bag or in any protected way (without any contact with the abdominal wall) via the umbilical port. Any fluid will be suctioned and washing performed if required. Fascial defects (10/12 trocars)will be closed with 2-O polydioxanone sutures and skin closed with 4-O non-absorbable sutures. No pelvic drain will be inserted. A three-band dressing will be applied in the end.

Also known as: Multiport Lap appendectomy

Conventional lap appendectomy

Eligibility Criteria

• Age: 5 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• patient age between 5-50 year old
• patient diagnosed as acute appendicitis

You may not qualify if:

• pregnacy
• perforated appendix
• severe obese patient
• previous abdominal exploration

Sponsors & Collaborators

• Abanoub Atif Fawzy: lead

MeSH Terms

Conditions

Appendicitis

Condition Hierarchy (Ancestors)

Intraabdominal Infections; Infections; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Cecal Diseases; Intestinal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principle investigator

Model Details: laparoscopic versus open appendectomy

Study Record Dates

• First Submitted: November 1, 2022
• First Posted: November 10, 2022
• Study Start: November 1, 2023
• Primary Completion: November 1, 2023
• Study Completion: November 1, 2024
• Last Updated: July 18, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share