NCT05610618

Brief Summary

This study aims to clarify the mechanisms by which the predictions we have about our visual environment influence the processing of expected or unexpected visual stimuli at the cerebral level.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 12, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 9, 2022

Completed
4 months until next milestone

Study Start

First participant enrolled

March 20, 2023

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2025

Completed
Last Updated

March 26, 2024

Status Verified

March 1, 2024

Enrollment Period

2 years

First QC Date

September 12, 2022

Last Update Submit

March 25, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Performance (% of correct classification) of a support vector machine algorithm in classifying the category of objects and scenes based on electroencephalography signals evoked by the visual perception of expected and unexpected objects and scenes

    We will use EEG data acquired while participants look at neutral objects and scenes of different categories to train a classifier in decoding the category of these objects and scenes. This classifier will then be tested using EEG data acquired while participants look at novel expected and unexpected objects and scenes. We will record the % accuracy of the classifier in this test phase.

    Through study completion, an average of 1.5 year

Study Arms (1)

Healthy adults

EXPERIMENTAL

A single group of healthy adults will undergo all experimental conditions (within subject design)

Other: Visual stimulation

Interventions

Participants will be displayed with photographs of scenes and objects which predictability and sharpness will be manipulated

Healthy adults

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Participants between 18 and 35 years old
  • Normal or corrected-to-normal visual acuity
  • Ability to consent or oppose to the research
  • No opposition to the research

You may not qualify if:

  • Important visual impairments
  • Neuropsychiatric pathology
  • Use of drug or medication with neurocognitive effects
  • Minors, or persons under psychiatric care, or protected persons

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Louise KAUFFMANN

Grenoble, Grenoble Cedex 9, 38043, France

RECRUITING

MeSH Terms

Interventions

Photic Stimulation

Intervention Hierarchy (Ancestors)

Physical StimulationInvestigative Techniques

Study Officials

  • Laurent VERCUEIL

    Grenoble Alpes University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 12, 2022

First Posted

November 9, 2022

Study Start

March 20, 2023

Primary Completion

March 1, 2025

Study Completion

March 1, 2025

Last Updated

March 26, 2024

Record last verified: 2024-03

Locations