Addiction and Acute Coronary Syndrome

NCT05605106 | Unknown

• 1 other identifier: addict ACS pts
• Study Type: observational
• Target: 72
• Locations: 0 countries
• Sites: N/A

Brief Summary

the study aims to

1. 1.identify the effect of addiction on TIMI flow in patients presented with acute coronary syndrome.
2. 2.identify the effect of addiction on outcomes of medical treatment of patients presenting with acute coronary syndrome.
3. 3.identify the relation between addiction and LV function.
4. 4.detect the effect of duration of addiction on myocardial infarction lesion and outcomes of pci.

Conditions

Acute Coronary Syndrome; Addiction

Outcome Measures

Primary Outcomes (2)

• Left ventricular systolic dysfunction in patients presenting with acute coronary syndrome

  Left ventricular systolic dysfunction is a common and serious complication of acute coronary syndrome that leads to increased risks of sudden death and of heart failure . in this study it will be measured using speckle tracking echocardiography.

  baseline

• Thrombolysis in Myocardial Infarction (TIMI) in patients undergoing PCI

  The TIMI Coronary Grade Flow is an effective and well-studied grading system of coronary reperfusion on an angiogram. Grade 0 means complete occlusion of the infarct-related artery Grade 1 means some penetration of contrast material beyond the point of obstruction but without perfusion of the distal coronary bed Grade 2 means perfusion of the entire infarct vessel into the distal bed but with delayed flow compared with a normal artery Grade 3 means full perfusion of the infarct vessel with normal flow

  baseline

Study Arms (2)

addict patients presenting with acute coronary syndrome

Diagnostic Test: speckle tracking echocardiography; Procedure: Percutaneous coronary intervention

non addict patients presenting with acute coronary syndrome

Diagnostic Test: speckle tracking echocardiography; Procedure: Percutaneous coronary intervention

Interventions

speckle tracking echocardiography DIAGNOSTIC_TEST

Speckle tracking is a recent development in image processing that uses proprietary software to automatically determine the movements of these points, which appear sonographically as "speckles," within the myocardium over time. Tracking the movements of these speckles throughout the cardiac cycle yields positive values when the two points are moving away from one another, as in diastole, and negative values when they are moving towards one another, as in systole

addict patients presenting with acute coronary syndrome; non addict patients presenting with acute coronary syndrome

Percutaneous coronary intervention PROCEDURE

Percutaneous coronary intervention refers to a family of minimally invasive procedures used to open clogged coronary arteries (those that deliver blood to the heart). By restoring blood flow, the treatment can improve symptoms of blocked arteries, such as chest pain or shortness of breath.

addict patients presenting with acute coronary syndrome; non addict patients presenting with acute coronary syndrome

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will include all patients presented with acute coronary syndrome in Assuit University Hospital .

You may qualify if:

• All patients of all categories of ages who will be presented with acute coronary syndrome in Assuit University Hospital .

You may not qualify if:

• Pateints presented with cardiogenic shock

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Acute Coronary Syndrome; Behavior, Addictive

Interventions

Percutaneous Coronary Intervention

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Compulsive Behavior; Impulsive Behavior; Behavior

Intervention Hierarchy (Ancestors)

Endovascular Procedures; Vascular Surgical Procedures; Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Officials

• Hossam El Araby, professor

  PRINCIPAL INVESTIGATOR

• Salma Taha, doctor

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mina Zaky, resident

CONTACT

+201270880164; gafeet90@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident doctor

Study Record Dates

• First Submitted: October 28, 2022
• First Posted: November 4, 2022
• Study Start: December 1, 2022
• Primary Completion: December 1, 2024
• Study Completion: February 1, 2025
• Last Updated: November 4, 2022

Record last verified: 2022-10