NCT05601583

Brief Summary

Eligible older adults with Type 2 Diabetes-Mild Cognitive Impairment (T2D-MCI) will be provided a Continuous Glucose Monitoring (CGM) device and asked to share CGM data with their care partners for daily decision-making for diabetes self-management. After 2 weeks, individual interviews will be conducted in 20 participants (10 dyads). Older adults with T2D-MCI (n=10) and their care partners (n=10) will be interviewed separately to identify key features of the Care Partner-Assisted Intervention through linking continuous glucose monitoring and Mobile Health (CP-CGMH) app.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for phase_1 type-2-diabetes

Timeline
16mo left

Started Apr 2023

Longer than P75 for phase_1 type-2-diabetes

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress70%
Apr 2023Aug 2027

First Submitted

Initial submission to the registry

October 27, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 1, 2022

Completed
6 months until next milestone

Study Start

First participant enrolled

April 19, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 29, 2023

Completed
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2027

Expected
Last Updated

October 15, 2025

Status Verified

October 1, 2025

Enrollment Period

4 months

First QC Date

October 27, 2022

Last Update Submit

October 13, 2025

Conditions

Keywords

Continuous Glucose Monitoring (CGM)

Outcome Measures

Primary Outcomes (3)

  • Technology Acceptance Subscale Score

    13-item questionnaire assessing participants' acceptance of the CGM technology. Items ranked on 7-point Likert scale ranging from 1-7. The total score is the sum of responses and ranges from 13 to 91; lower scores indicate greater overall acceptance.

    Day 14

  • Total CGM Use Time

    Up to Day 14

  • Total Scan Time

    Patients can use the reader or their personal smartphone to scan the CGM sensor to get the real-time glucose values.

    Up to Day 14

Study Arms (1)

CP-CGMH

EXPERIMENTAL

CP-CGMH: Care Partner-Assisted Intervention through linking continuous glucose monitoring and Mobile Health. Participants will receive a CGM device and asked to share CGM data with their care partners for daily decision-making for diabetes self-management for two weeks. The LibreLinkup mHealth app will be used to share data.

Device: Continuous Glucose Monitor (CGM)

Interventions

FDA-cleared FreeStyle Libre Glucose Monitoring System manufactured by Abbott. Integrated continuous glucose monitoring system that provides continuous glucose measurements every minute to provide glucose levels, trends and alerts.

Also known as: Freestyle Libre CGM
CP-CGMH

Eligibility Criteria

Age65 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Older adults must meet all of the following criteria:
  • be ≥ 65 years old;
  • have had a diagnosis of T2D for at least one year;
  • have MCI, defined as score 19-25 on the Montreal Cognitive Assessment (MoCA);60,61
  • have a care partner (e.g., spouse or adult children);
  • be willing to use CGM;
  • be fluent in English.
  • Eligible care partners must be:
  • ≥ 18 years old;
  • living with older adults with T2D-MCI;
  • willing to be involved in patients' daily care;
  • fluent in English.

You may not qualify if:

  • Older adults who meet any of the following criteria will be excluded from participation in this study:
  • Refuse or are unable to provide informed consent;
  • Have serious physical illness (e.g., end-stage renal disease);
  • Presence of mental illness (e.g., schizophrenia or bipolar disorder) that would preclude participation.
  • The care partners will be excluded if they:
  • Refuse or are unable to provide informed consent;
  • Have MCI.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bellevue Hospital

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesCognition DisordersNeurocognitive DisordersMental Disorders

Study Officials

  • Yaguang Zheng, PhD, RN

    Rory Meyers College of Nursing

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 27, 2022

First Posted

November 1, 2022

Study Start

April 19, 2023

Primary Completion

August 29, 2023

Study Completion (Estimated)

August 31, 2027

Last Updated

October 15, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will share

The de-identified participant data from the final research dataset used in the published manuscript will be shared upon reasonable request beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research provided the investigator who proposes to use the data executes a data use agreement with NYU Langone Health. Requests may be directed to: Yaguang.zheng@nyu.edu. The protocol and statistical analysis plan will be made available on Clinicaltrials.gov only as required by federal regulation or as a condition of awards and agreements supporting the research.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research.
Access Criteria
The investigator who proposed to use the data will have access to the data upon reasonable request. Requests should be directed to Yaguang.zheng@nyu.edu. To gain access, data requestors will need to sign a data access agreement.

Locations