Background of Different Phenotypes of Coeliac Disease
Genetic and Biological Background and Follow-up of Different Phenotypes of Coeliac Disease
Genetic and Biological Background and Follow-up of Different Phenotypes of Coeliac Disease
Sponsor study identifier
observational
3,500
1 country
1
Study Start
November 8, 2022
Actual (reported)Primary Completion
December 31, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 31, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The main purpose of this study is to investigate genetic, serological, immunological and microbiata diversities between different coeliac disease phenotypes and to discover applicable prognostic markers for specific phenotypes.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 31, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 3, 2022
Actual (reported)October 28, 2022
Actual (reported)November 8, 2022
Actual (reported)December 31, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
December 31, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Non-HLA variant association
phenotype specific non-HLA variants
baseline
serum transglutaminase antibodies
baseline
microbiata
baseline
quality of life measure
baseline
gastrointestinal symptoms
baseline
dietary adherence
baseline
Adult (18 years or over) patients with previous coeliac disease or dermatitis herpetiformis diagnosis
500 adult (18 years or over) friends or non-related family members of coeliac disease or dermatitis herpetiformis patients participating in the study, no previous coeliac disease or dermatitis herpetiformis diagnosis. In addition 1000 controls will be included from Biobank
Assessment of genetic predisposition to various celiac disease phenotypes. No intervention.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
National and also focused recruitment for patients with coeliac disease or dermatitis herpetiformis diagnosis. Healthy controls recruited via volunteered subjects with coeliac disease or dermatitis herpetiformis
Tampere University Hospital
Tampere, 33521, Finland
First Submitted
October 3, 2022
First Posted
October 28, 2022
Study Start
November 8, 2022
Actual (reported)Primary Completion
December 31, 2027
EstimatedImpact of the Diagnosis of Celiac Disease
Contact the study team to confirm eligibility.
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 31, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
September 17, 2025
Record last verified: 2025-09
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Source: ClinicalTrials.gov.
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