NCT05581537

Brief Summary

Stroke is the leading cause of disability in the elderly . The most common manifestations of stroke are deficits in motor control that involve abnormal synergistic organization of movements, muscle weakness, sensory deficits, and loss of range of motion. Poor posture, which is one of its main symptoms, affects falls or injured falls. Fear of falling is a psychological condition associated with balance disorders and fall risks after a stroke.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Jul 2022

Typical duration for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2022

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

July 17, 2022

Completed
3 months until next milestone

First Posted

Study publicly available on registry

October 14, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2024

Completed
Last Updated

November 22, 2022

Status Verified

November 1, 2022

Enrollment Period

1.1 years

First QC Date

July 17, 2022

Last Update Submit

November 21, 2022

Conditions

Outcome Measures

Primary Outcomes (3)

  • Dynamic Gait Index

    the DGI tests the ability of the participant to maintain walking balance while responding to different task demands, through various dynamic conditions. It is a useful test in individuals with vestibular and balance problems and those at risk of falls. It includes eight items, walking on level surfaces, changing speeds, head turns in horizontal and vertical directions, walking and turning 180 degrees to stop, stepping over and around obstacles, and stair ascent and descent. Each item is scored on a scale of 0 to 3, with 3 indicating normal performance and 0 representing severe impairment. The best possible score on the DGI is a 24

    1 year

  • Berg Balance Scale

    is used to objectively determine a patient's ability (or inability) to safely balance during a series of predetermined tasks. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function and takes approximately 20 minutes to complete. It does not include the assessment of gait.

    1 year

  • Falls Efficacy Scale - International (FES-I)

    It is a 16 item questionnaire, useful to the researchers and clinicians interested in fear of falling, with a score ranging from minimum 16 (no concern about falling) to maximum 64 (severe concern about falling)

    1 year

Study Arms (2)

Study group (GA)

EXPERIMENTAL

receive systematic desensitization in addition to goal directed paradigm for eight weeks, Three sessions per week (1hour and half)

Other: Systematic Desensitization

Control group (GB)

EXPERIMENTAL

receive goal directed paradigm for eight weeks, Three sessions per week (45 minutes)

Other: Systematic Desensitization

Interventions

Systematic desensitization: 2 techniques 1. Jacobson's technique (progressive muscle relaxation): It involves tensing and releasing muscles that progress through the body throughout focusing on mental relaxation throughout releasing muscle tension 2. Guided imagery (vividly imagining): It includes 2 types of imagery training/mental practice (MP) which includes visual imagery is based on the sensory (visual) perception of the imagined movement and Kinesthetic imagery is based on sensory-motor information (proprioceptive). MP will be conducted in a quiet room, where each patient will be given detailed instructions to perform both visual and kinesthetic practice

Also known as: Goal directed paradigm
Control group (GB)Study group (GA)

Eligibility Criteria

Age45 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Both genders will be involved
  • Duration of the disease is more than 3 months.
  • Ischemic and hemorrhagic stroke will be included
  • Left sided hemiparesis
  • Hemiparetic patient, degree of spasticity for upper and lower limbs ranges from (grade 1+ : 2 ) according to modified Aschworth scale
  • Patient's age ranges from 45 to 60 years.
  • Patient's ability to stand independently for at least 5 minutes without the use of an assistive device.
  • Patients with sufficient cognitive abilities that enables them to understand and follow instructions (The Montreal Cognitive Assessment score \>26) (Appendix II).
  • Body mass index for patients will not be more than 30.

You may not qualify if:

  • Neurological diseases that affect gait other than stroke (eg: Multiple sclerosis, Peripheral neuropathy, Parkinsonism etc.).
  • Musculoskeletal disorders such as severe arthritis, knee surgery, total hip joint replacement, lower limb fractures less than 6 months or contractures of fixed deformity, leg length discrepancy.
  • Cardiovascular problems (unstable angina, recent myocardial infarction within the last three months, congestive heart failure, significant heart valve dysfunction, or unstable hypertension) or pulmonary disorders.
  • Visual, auditory and speech problems.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

October 6 University

Giza, Egypt

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Lecturer

Study Record Dates

First Submitted

July 17, 2022

First Posted

October 14, 2022

Study Start

July 1, 2022

Primary Completion

August 1, 2023

Study Completion

July 1, 2024

Last Updated

November 22, 2022

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share

Locations