NCT05566171

Brief Summary

Probiotics have beneficial effect on Gastrointestinal Symptoms. The aim of this study is to determine the effect of probiotic yogurt consumptions on the people who have gastrointestinal symptoms mainly constipation.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Sep 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 4, 2022

Completed
1.9 years until next milestone

Study Start

First participant enrolled

September 1, 2024

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2025

Completed
Last Updated

August 12, 2025

Status Verified

August 1, 2025

Enrollment Period

4 months

First QC Date

September 30, 2022

Last Update Submit

August 7, 2025

Conditions

Gastrointestinal Dysfunction

Keywords

probiotic, gastrointestinal symptoms, constipation

Outcome Measures

Primary Outcomes (1)

  • The severity of gastrointestinal symptoms (mainly constipation) will decrease in the interventional group

    We expect to see improvement in the gastrointestinal symptoms after consuming probiotic yogurt

    4 weeks

Study Arms (2)

Control Group

NO INTERVENTION

This group will be just follow-up for 4 weeks without any intervention

Interventional Group

EXPERIMENTAL

This group will consume 125 g plain Activia Probiotic Yogurt without any aroma/fruit during 4 weeks/1 month

Dietary Supplement: Activia Probiotic Yogurt

Interventions

Activia Probiotic YogurtDIETARY_SUPPLEMENT

Activia probiotic Yogurt will be consumed by participants in this group

Interventional Group

Eligibility Criteria

Age19 Years - 64 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Living in Izmir
  • Individuals who are having BMI between 18.5-24.9 kg / m2
  • Having gastrointestinal symptoms according to Constipation Severity Scale and Bristol Stool Scale

You may not qualify if:

  • Having diagnosed gastrointestinal disease
  • Regular consumption of probiotic
  • Using of drug that affects gastrointestinal system
  • Presence of mental illness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nezire

Famagusta, 99520, Cyprus

Location

MeSH Terms

Conditions

Constipation

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Nezire Ince

    Eastern Mediterranean University

    STUDY DIRECTOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Asst. Prof.

Study Record Dates

First Submitted

September 30, 2022

First Posted

October 4, 2022

Study Start

September 1, 2024

Primary Completion

December 30, 2024

Study Completion

March 30, 2025

Last Updated

August 12, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations

CY(1)