The Effect of Embryo Transfer Technique on Pregnancy Outcomes in HRT-FET Cycles
1 other identifier
observational
600
1 country
1
Brief Summary
The positions of the air bubble and the tip of catheter will be measured by transabdominal utrasonography among patients who have undergone high-quality frozen blastocyst transfer. The aim of this study is to compare pregnancy rates according to air bubble's final location in endometrial cavity. It is expected that the ET technique will be improved and live birth rates will increase by determining the optimal position of the embryo in the endometrial cavity during ET in patients who have achieved pregnancy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2021
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2021
CompletedFirst Submitted
Initial submission to the registry
September 29, 2022
CompletedFirst Posted
Study publicly available on registry
October 3, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedMay 23, 2023
May 1, 2023
1.7 years
September 29, 2022
May 20, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Positive β-hCG results
Positive β-hCG results nine days after embryo transfer.
Nine days after each embryo transfer
Study Arms (2)
non-pregnant
Negative b-hCG results 9 days after embryo transfer.
pregnant
Positive b-hCG results 9 days after embryo transfer.
Interventions
During embryo transfer in each patient, endometrial thickness, uterine cavity dimensions, distance of transfer catheter to the fundus, distance of released air bubble to the fundus, and distance of air bubble to side walls will be systematically measured and recorded under the guidance of transabdominal ultrasonography.
Eligibility Criteria
All patients who have artificial endometrial preparation with high-quality blastocysts between December 2021 and December 2022 will be included.
You may qualify if:
- Exogenous hormone preparation of the endometrial lining
- High embryo quality ((≥2BB) according to Alpha criteria
- Embryo transfer at the blastocyst stage
You may not qualify if:
- Patients whose treatments were canceled for any reason before the embryo transfer procedure
- Patients who underwent embryo transfer in the cleavage stage
- Presence of low-quality (\<2BB) blastocysts
- \>15% loss of viability of the embryo during embryo thawing,
- Patients with congenital uterine malformations,
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Akdeniz University
Antalya, 07700, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
ŞAFAK OLGAN, MD
Akdeniz University
- STUDY CHAIR
ARİF C ÖZSİPAHİ, MD
Akdeniz University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
September 29, 2022
First Posted
October 3, 2022
Study Start
December 1, 2021
Primary Completion
August 1, 2023
Study Completion
December 31, 2023
Last Updated
May 23, 2023
Record last verified: 2023-05