Effect of Herbal Formulation on Thrombocytes Count

NCT05563064 | Unknown Phase 3 DMC

• 1 other identifier: Shayan Fatima
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Effect of Herbal Formulation Karika Syrup on Thrombocyte Count.

Conditions

Thrombocytopenia

Keywords

Thrombocyte Count, Karika

Outcome Measures

Primary Outcomes (1)

• EFFECT OF HERBAL FORMULATION KARIKA SYRUP ON THROMBOCYTE COUNT

  This study is designed to check or confirm the Karika syrup efficacy for increasing the platelet count, its anti-inflammatory and anti-pyretic actions. This medicinal use of Karika will be confirmed through clinical studies in patients with low platelet count associated with dengue, typhoid, malaria, viral fever\& chikungunya fever.9 It is based on the interpretations as generated from CBC by analyzing it on SPSS. 10 It is research-based open, randomized clinical trial on 72 subjects Multi-centered: Karachi (Kalaboard, Jafar-e-tyyar) and Interior Sindh (Kapri Mori).

  3 years

Study Arms (1)

Karika Syrup

EXPERIMENTAL

Karika syrup has been used to treat thrombocytopenia

Drug: Karika Syrup

Interventions

Karika Syrup DRUG

To evaluate the effects of Karika syrup on complete blood count specifically thrombocytes (platelets) collected from blood samples of patients after treatment of 15 days long period.

Karika Syrup

Eligibility Criteria

• Age: 14 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Female and Male patients of age 14 to 60 years.
• Patient suffering from complaints of Weakness, Fatigue, Puerperal Rashes, Shortness of Breath, Low Hemoglobin, and History of Fever on \& off, Epistaxis.18
• Patients from Karachi and Kapri Mori(Labors, Employed, Multigravida females, Housewives, Domestic helpers, Working women, School, College, and University Students).
• All socioeconomic classes are included in the study.
• Patients having a history of Covid-19, Viral fever, Typhoid, and other illnesses in which there has been a low platelet count.2

You may not qualify if:

• Pregnant females are excluded.17
• Patients with co-morbidities like uncontrolled hypertension and liver disorder are excluded.4,5,6
• Patient having known drug reaction from any content of formulation is excluded.7
• Patients suffering from serious illnesses like encephalitis, coma, meningitis, or head injury that make them bedridden or hospitalized are excluded.4,6

Sponsors & Collaborators

• Shifa Ul Mulk Memorial Hospital: lead

Study Sites (1)

Pakistan

Karachi, Sindh, Pakistan

RECRUITING

MeSH Terms

Conditions

Thrombocytopenia

Condition Hierarchy (Ancestors)

Blood Platelet Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Cytopenia

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chairperson Department of Eastern Medicine, Jinnah University

Model Details: A randomized, open, prospective, multicenter clinical trial to evaluate the effects of Karika syrup on complete blood count specifically thrombocytes (platelets)

Study Record Dates

• First Submitted: September 28, 2022
• First Posted: October 3, 2022
• Study Start: January 1, 2021
• Primary Completion: January 1, 2023
• Study Completion: January 1, 2023
• Last Updated: October 4, 2022

Record last verified: 2022-10

Locations

PA (1)