NCT05554081

Brief Summary

This study aims specifically to compare the rates of contaminants between standard clean-catch urine collection and urine collected using the PEEZY device. In particular, this study will compare the rates of contamination as stratified by BMI status (i.e., BMI \< 30 and BMI ≥30). Based on previous studies through LUHS and the Wolfe lab, we anticipate a reduction in contamination from sample collected using the PEEZY device, particularly among those pregnant women with BMI ≥30. To investigate this hypothesis we have designed a prospective unblinded randomized controlled trial comparing voided urine specimens obtained for asymptomatic bacteriuria in pregnant women presenting for obstetric care with use of standard clean-catch (CC) sampling method versus specimen obtained using PEEZY collection device.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 21, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 26, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2024

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2024

Completed
Last Updated

October 9, 2024

Status Verified

October 1, 2024

Enrollment Period

1.4 years

First QC Date

September 21, 2022

Last Update Submit

October 7, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Urine contamination rates

    1\. To compare the rates of contaminants between CC and PEEZY samples stratified by BMI status (i.e., BMI \< 30 and BMI ≥30)

    August 2022-August 2023

Secondary Outcomes (1)

  • Maternal comorbidities and contamination

    August 2022-August 2023

Study Arms (4)

Clean catch BMI < 30

PLACEBO COMPARATOR

Standard of care urine collection

Device: Peezy urine collection device

Clean catch BMI > 30

PLACEBO COMPARATOR

Standard of care urine collection

Device: Peezy urine collection device

PEEZy collection BMI < 30

EXPERIMENTAL

PEEZY device for urine collection

Device: Peezy urine collection device

PEEZY collection BMI > 30

EXPERIMENTAL

PEEZY device for urine collection

Device: Peezy urine collection device

Interventions

use peezy collection to obtain urine sample

Clean catch BMI < 30Clean catch BMI > 30PEEZY collection BMI > 30PEEZy collection BMI < 30

Eligibility Criteria

Age18 Years+
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Pregnant \< 20 weeks gestational age
  • Age \> 18 years old
  • English speaking

You may not qualify if:

  • History of recurrent UTIs
  • Need for ongoing antibiotics
  • Urinary tract anomalies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Loyola University medical Center

Maywood, Illinois, 60153, United States

Location

MeSH Terms

Conditions

Urinary Tract Infections

Condition Hierarchy (Ancestors)

InfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

September 21, 2022

First Posted

September 26, 2022

Study Start

August 1, 2022

Primary Completion

January 1, 2024

Study Completion

October 31, 2024

Last Updated

October 9, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

Locations