Modified Reporting of Positive Urine Cultures Collected From Long Term Care

NCT03554603 | Completed Results

• 1 other identifier: MUN-04
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the laboratory for culture results. The restricted report may reduce the rate of inappropriate treatment of AB.

Conditions

Urinary Tract Infections; Asymptomatic Bacteriuria

Keywords

Long term care; Urine culture

Outcome Measures

Primary Outcomes (1)

• Proportion of Asymptomatic Bacteriuria Treated With Antibiotics and Urinary Tract Infection Treated With Antibiotics

  Number of Participants Who Received Appropriate Antibiotic Treatment

  7 days

Study Arms (2)

Modified Reporting

EXPERIMENTAL

Microbiology laboratory will report "Positive urine cultures may represent asymptomatic bacteriuria or urinary tract infection. If urinary tract infection is suspected clinically, please call 777-xxxx (researcher mobile phone) for identification and susceptibility results"

Behavioral: Modified Report

Standard Reporting

NO INTERVENTION

Microbiology laboratory will report identification and susceptibility results

Interventions

Modified Report BEHAVIORAL

An abbreviated version of the microbiology report indicating that growth is present and the physician should call the lab for further details if clinically important.

Also known as: Restricted Report

Modified Reporting

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• \. Consecutive positive urine cultures collected from patients admitted to Long term care facilities will be included. All methods of urine collection will be included (midstream, in-and-out catheterization, indwelling catheter).

You may not qualify if:

• Positive urine cultures not collected from Long term care facility patients
• Pregnancy
• Antibiotic treatment at the time of collection
• Patients known to have blood neutrophils \<1.0 within 7 days of urine collection

Sponsors & Collaborators

• Memorial University of Newfoundland: lead

Study Sites (1)

Health Sciences Center

St. John's, Newfoundland and Labrador, A1B3V6, Canada

Location

MeSH Terms

Conditions

Urinary Tract Infections

Condition Hierarchy (Ancestors)

Infections; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Results Point of Contact

• Title: Peter Daley MD MSc
• Organization: Memorial University

pkd336@mun.ca

7097772089

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 1, 2018
• First Posted: June 13, 2018
• Study Start: November 5, 2018
• Primary Completion: July 31, 2019
• Study Completion: July 31, 2019
• Last Updated: March 1, 2024
• Results First Posted: March 1, 2024

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)