Diagnostic of Rotator Cuff Calcific Tendinosis Using MRI With ZTE Sequence

NCT05553535 | Unknown

• 1 other identifier: N°1-RCB/EUDRACT
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Conventional radiographs are still considered the reference for identifying rotator cuff calcific tendinosis. MRI is widely performed for rotator cuff disorders evaluation but has a moderate accuracy in rotator cuff calcific tendinosis diagnosis and calcific deposits identification (sensitivity and specificity around 60%), even though it helps in determining acuity of the finding by adjacent soft tissue edema depiction and differential diagnosis identification (i.e. adhesive capsulitis, sub-acromial bursitis…). Zero echo time (ZTE) MRI provides enhanced bone contrast by enabling the acquisition of signals from tissues exhibiting the shortest T2 values on a single sequence with a spatial resolution of 0.8-1.2 mm isotropic and can therefore provide images similar to those obtained with radiographs. We hypothesize that ZTE images could also depict rotator cuff calcific tendinosis, but to our knowledge, no study compared this technique to radiographs and/or standard MRI.

Conditions

Cuff Rotator Tendinitis

Outcome Measures

Primary Outcomes (1)

• calcific deposits presence

  presence of signal hyperintensity within the tendon on MRI ZTE sequence

  Retrospective review of all MRI scans, performed at a maximum of 1 year before the reading, during two reading sessions, with an interval of 15 days, in october and november 2022

Study Arms (2)

cases

cases of rotator cuff calcific tendinosis on imaging studies

Diagnostic Test: MRI

witnesses

differential diagnosis or normal cases

Diagnostic Test: MRI

Interventions

MRI DIAGNOSTIC_TEST

retrospective review of shoulder MRI

cases; witnesses

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients over 18 years old referred to our department for a suspicion of rotator cuff tendinosis

You may qualify if:

• patient referred to the imaging department for a MRI scan in case of suspicion of rotator cuff tendinosis

You may not qualify if:

• incomplete data sets

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Related Publications (2)

• Norenberg D, Ebersberger HU, Walter T, Ockert B, Knobloch G, Diederichs G, Hamm B, Makowski MR. Diagnosis of Calcific Tendonitis of the Rotator Cuff by Using Susceptibility-weighted MR Imaging. Radiology. 2016 Feb;278(2):475-84. doi: 10.1148/radiol.2015150034. Epub 2015 Sep 3.

  PMID: 26347995 BACKGROUND

• Aydingoz U, Yildiz AE, Ergen FB. Zero Echo Time Musculoskeletal MRI: Technique, Optimization, Applications, and Pitfalls. Radiographics. 2022 Sep-Oct;42(5):1398-1414. doi: 10.1148/rg.220029. Epub 2022 Jul 29.

  PMID: 35904982 BACKGROUND

MeSH Terms

Conditions

Rotator Cuff Injuries

Condition Hierarchy (Ancestors)

Rupture; Wounds and Injuries; Shoulder Injuries; Tendon Injuries

Central Study Contacts

romain gillet, MD

CONTACT

0680987216; romain_gillet3@hotmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: September 19, 2022
• First Posted: September 23, 2022
• Study Start: October 1, 2022
• Primary Completion: October 1, 2022
• Study Completion: November 1, 2022
• Last Updated: September 23, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share