The Application of Neuromodulation in Sciatic Nerve

NCT05549700 | Completed

• 1 other identifier: Sciatic nerve and NMP
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study will be to analyze the muscle activity of the short head (SHBF) and long head of the biceps femoris (LHBF) after the application of ultrasound-guided percutaneous neuromodulation (NMP) in the tibial or common fibular nerve compartment of the sciatic nerve. Authors will recruit healthy subjects and they will receive asymmetric biphasic rectangular current through a needle into the sciatic nerve. The sample was divided into two groups: one to which the technique was applied in the lateral compartment and another group, in the medial compartment of the nerve. The protocol used was 5 seconds of stimulation, 55 seconds of rest for 5 minutes at a frequency of 100 Hz and a phase duration of 350 microseconds. The electrical activity (recruitment of muscle fibers and maximum contraction) of the SHBF and LHBF and the muscle strength of the knee flexors were recorded by requesting the participants isometric flexion of the knee in the prone position. The percentage of change of each variable was also analyzed.

Conditions

Healthy

Outcome Measures

Primary Outcomes (2)

• Electrical muscular activity

  recruitment of muscle fibers, measured by electromyography (microvolts)

  3 months

• muscle strength of the knee flexors

  strength measured by dynamometer (Kg)

  3 months

Study Arms (2)

Common fibular nerve group

EXPERIMENTAL

The subjects of this group will receive electric nerve stimulation on the sciatic nerve through a lateral approach to stimulate the behavior corresponding to the common fibular nerve

Other: Neuromodulation

Tibial nerve group

EXPERIMENTAL

The subjects of this group will receive electric nerve stimulation on the sciatic nerve through a lateral approach to stimulate the behavior corresponding to the tibial nerve

Other: Neuromodulation

Interventions

Neuromodulation OTHER

Ultrasound-guided percutaneous neuromodulation will be applied. The protocol used was 5 seconds of stimulation, 55 seconds of rest for 5 minutes at a frequency of 100 Hz and a phase duration of 350 microseconds

Common fibular nerve group; Tibial nerve group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy volunteer

You may not qualify if:

• Subjects that have lumbar area of the back, scoliosis, lower limb dysmetria
• Subjects undergone any surgical intervention in the lumbar area or lower limbs
• Subjects that present acute or unresolved injury in the last 6 months in the lower limbs
• Subjects under treatment drug treatment
• Subjects that they are afraid of needles or electric current
• Subjects with epileptic
• Pregnant.

Sponsors & Collaborators

• University of Seville: lead

Study Sites (1)

Blanca

Seville, Sevile, 41009, Spain

Location

Related Publications (1)

• Paez-Rodriguez J, Olivo-Ruiz I, Romero-Morales C, De-la-Cruz-Torres B. The fascicular anatomy of the sciatic nerve may not influence the muscular activity of the biceps femoris after applying percutaneous electrical nerve stimulation: a randomized clinical trial. Acupunct Med. 2024 Dec;42(6):326-333. doi: 10.1177/09645284241300176. Epub 2024 Nov 21.

  PMID: 39569806 DERIVED

MeSH Terms

Interventions

Transcutaneous Electric Nerve Stimulation

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Physical Therapy Modalities; Rehabilitation; Analgesia; Anesthesia and Analgesia

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: September 15, 2022
• First Posted: September 22, 2022
• Study Start: December 1, 2022
• Primary Completion: December 2, 2022
• Study Completion: December 30, 2022
• Last Updated: January 4, 2023

Record last verified: 2022-12

Locations

ES (1)