NCT05549687

Brief Summary

This trial studies how well an electronic (e)-health support program, called the PACK Health Program, supports patient reported symptoms in newly diagnosed patients with breast cancer. PACK Health offers a symptom management program involving both interpersonal interaction, as well as e-modules for patients diagnosed with cancer to better manage pain, fatigue, depression, anxiety, and to navigate care more effectively through e-health coaching and tools. Participating in the PACK Health Program may support breast cancer patients' reported side effects and experience of care during chemotherapy treatment and may ultimately improve overall health.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
419

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 19, 2017

Completed
5.3 years until next milestone

First Submitted

Initial submission to the registry

September 7, 2022

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 22, 2022

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 7, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 7, 2023

Completed
Last Updated

August 14, 2023

Status Verified

August 1, 2023

Enrollment Period

6.2 years

First QC Date

September 7, 2022

Last Update Submit

August 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Impact of electronic (e)-health support program on patient reported outcomes

    Measured with the National Institutes of Health Patient Reported Outcomes Measurement Information System (PROMIS) Global Health Scale. Summary statistics and box plots will be used to describe PROMIS scores by intervention arm and assessment time. A 2-sample t-test will be used to compare PROMIS scores at 3 months between intervention groups. Linear mixed effects models (LMMs) will be used to assess PROMIS scores over time. The models will include assessment time, intervention and baseline score as fixed effects and intercept as a random effect. Additional models will be created to include possible confounding covariates. PROMIS instrument scores will be reviewed and patients referred to the primary medical team if they score 1 on items 1-6, and 9, indicating poor health state and 4 or greater on items 8 and 10, indicating potential emotional distress or moderate to severe fatigue.

    Baseline up to 3 months

Study Arms (2)

Group I (Pack Health Program)

EXPERIMENTAL

Patients participate in the Pack Health Program which includes up to 60 scheduled touch points via phone, text, email and a mobile application and weekly interaction with a health coach over 3 months. They also have access to standard of care support services at MD Anderson including a telephone triage line 5 days a week between 8 a.m. and 5 p.m.

Other: Questionnaire AdministrationProcedure: Supportive Care

Group II (standard of care support services)

ACTIVE COMPARATOR

Patients receive standard of care support services with a telephone triage line available 5 days a week between 8 a.m. and 5 p.m.

Other: Questionnaire AdministrationProcedure: Supportive Care

Interventions

Ancillary studies

Group I (Pack Health Program)Group II (standard of care support services)

Participate in Pack Health, an electronic support program

Group I (Pack Health Program)

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English speaking.
  • Newly diagnosed women with a breast cancer diagnosis preparing to undergo chemotherapy for the first time.
  • All chemotherapy treatment to be completed at the study institution.
  • Access to electronic resources, defined for the purposes of this study as a mobile phone, a landline phone, a computer, or another device with the capacity to receive calls, texts, or e-mails.

You may not qualify if:

  • Patients who have received previous chemotherapy treatment for cancer.
  • Patients who are unable to verbalize (e.g. due to tracheostomy).
  • Patients enrolled on Protocol 2016-0300, as these patients will be receiving proactive triage calls from nurses that could skew their symptom reporting.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Palliative Care

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Eileen Hacker, PHD

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2022

First Posted

September 22, 2022

Study Start

May 19, 2017

Primary Completion

August 7, 2023

Study Completion

August 7, 2023

Last Updated

August 14, 2023

Record last verified: 2023-08

Locations