The Oral Biomechanical Functions of Hong Kong Healthy Adults

NCT05549648 | Completed

• 1 other identifier: UW21-324
• Study Type: interventional
• Target: 92
• Locations: 1 country
• Sites: 1

Brief Summary

Hong Kong and Japan are similar in terms of facing the super-ageing society. Maintaining oral function in elderly is particularly important because it affects social, physical and mental health to the people and to the society. By using technology seems to be one of the solutions in dealing with this. Thus, this project aims at using state-of-the-art Age-tech that have been used in Japan to implement "Oral Frailty" concept in Hong Kong. Through identifying oral biomechanical in elderly population, the investigators expect the situation can be improved, and the data analysed and collected can be useful and impactful that can influence the dental communities around Southeast Asia and the globe.

Conditions

Oral Manifestations

Keywords

oral frailty; oral muscle; home oral exercise

Outcome Measures

Primary Outcomes (5)

• Occlusal force assessment

  The tooth models and occlusion will be taken to record the occlusal contact point, area and distribution, by intra-oral scanner (CEREC Omniscan / 3Shape), which is a standard practice at HKU. The occlusal force (N), occlusal contact area (mm2), maximum occlusal pressure (MPa), average occlusal pressure (MPa) of both sides are measured respectively, using occlusal pressure measurement film (Dental Prescale® II 50H, GC Corp) that is scanned with a dedicated scanner (GT-X830, Epson) with analysis software (Bite force analyzer, GC Corp).

  The 1, 30, 90, and 120 days after recruitment. The investigators wanted to see if exercise would help oral muscle performance, there's a lack of data on this, so the investigator couldn't determine a change over time.

• Masticatory efficiency

  Gluco sensor (GS-II, GC Corp) will be used to quantitatively analyze the chewing ability 1. Rinse mouth for 3 times, 20s at least for each time. 2. Insert the test stick into GS-2, power on, and wait 6 seconds. 3. Chewing for 20s, use the preferred chewing side. 4. Rinse mouth with 10ml pure water and spit into the paper cup with a blue filter. 5. Discard the jelly residue in the filter, mix up the liquid (10s), dip the solution with a micro brush, point it on the test stick, wait for 6s for result reading, record reading: the concentration of sugar: \_\_\_\_mg/dL.

  The 1, 30, 90, and 120 days after recruitment. The investigators wanted to see if exercise would help oral muscle performance, there's a lack of data on this, so the investigator couldn't determine a change over time.

• Tongue function assessment

  Tongue pressure sensor (TPM-02, GC Corp) which indicates the tongue physical function, will be used to record the maximum tongue pressure (MPa) for 3 times of each participant, then tongue endurance will also be measured for 3 times by determining how long tongue could sustain 60% of their maximal pressure.

  The 1, 30, 90, and 120 days after recruitment. The investigators wanted to see if exercise would help oral muscle performance, but there's a lack of data on improving this function, so the investigator couldn't determine a change over time.

• Dry mouth

  A Chinese (Cantonese) version of dry mouth questionnaire consisting of 8-item xerostomia questions with a maximum total score of 32 points was used for subjective assessment, using a Likert format rated on a 4-point scale (1 not at all, 4 very much). Participants graded each aspect, with a higher score indicating impaired salivary function

  The 1, 30, 90, and 120 days after recruitment.

• Oral health-related quality of life

  The Chinese-validated version of the Oral Health Impact Profile-14 (OHIP-14) questionnaire was used to assess oral health-related quality of life, using a Likert format rated on a 5-point scale (0 not at all, 4 very much) for 14 questions, higher scores represent the poorer oral condition-related quality of life, with a minimum 0 points and maximum 56 points.

  The 1, 30, 90, and 120 days after recruitment.

Secondary Outcomes (2)

• Swallowing function assessment

  The 1, 30, 90, and 120 days after recruitment. The investigators wanted to see if exercise would help oral muscle performance, there's a lack of data on this, so the investigator couldn't determine a change over time.

• DDK rate

  The 1, 30, 90, and 120 days after recruitment. The investigators wanted to see if exercise would help oral muscle performance, there's a lack of data on this, so the investigator couldn't determine a change over time.

Study Arms (1)

Self-controlled Study

OTHER

Hong Kong citizens over 50 years old

Other: Home oral excrise

Interventions

Home oral excrise OTHER

The current study aimed to evaluate the efficacy and user experience of mobile phone APP, a mobile application with AI component in facial movement tracking, in improving oral functions of elderly people

Self-controlled Study

Eligibility Criteria

• Age: 50 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Population with aged (50-90 y.o.) neurologically healthy citizens in Hong Kong who have at least 1 occluding paired molars.
• Can read Traditional Chinese and communicate in Cantonese
• Possessed a smartphone with internet access and was able to use it on their own or with the help of at least one family member
• passed the Montreal Cognitive Assessment 5-Minute Protocol (Hong Kong Version)

You may not qualify if:

• Subject who was under 50 or unable to give consent.
• Subject who has Cerebrovascular accident, Head and Neck Cancers, Neurologic Diseases, and other severe systemic diseases.
• Subject who is receiving radiotherapy and chemotherapy.
• Subject who was medically unfit.
• Subject who has no molar.

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

Faculty of Dentisry, the University of Hong Kong

Hong Kong, Hong Kong SAR, 000000, Hong Kong

Location

Related Publications (11)

• Johnston, L. What fast-ageing countries such as china tell us about our economic future. CommonWealth Magazine 2019.

  BACKGROUND

• Libicki, M.C.; Shatz, H.J.; Taylor, J.E. The economic burden of aging populations. In Global demographic change and its implications for military power, RAND Corporation: 2011; pp 59-82.

  BACKGROUND

• Hong kong population projections 2020-2069. The Government of HKSAR: Hong Kong, 2020.

  BACKGROUND

• Rodrigues HL Jr, Scelza MF, Boaventura GT, Custodio SM, Moreira EA, Oliveira Dde L. Relation between oral health and nutritional condition in the elderly. J Appl Oral Sci. 2012 Feb;20(1):38-44. doi: 10.1590/s1678-77572012000100008.

  PMID: 22437676 BACKGROUND

• Nitschke I, Muller F. The impact of oral health on the quality of life in the elderly. Oral Health Prev Dent. 2004;2 Suppl 1:271-5.

  PMID: 15646585 BACKGROUND

• Pillai RS, Iyer K, Spin-Neto R, Kothari SF, Nielsen JF, Kothari M. Oral Health and Brain Injury: Causal or Casual Relation? Cerebrovasc Dis Extra. 2018;8(1):1-15. doi: 10.1159/000484989. Epub 2018 Jan 9.

  PMID: 29402871 BACKGROUND

• Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz K, Hasturk H, Walker GD, Reynolds EC, Faull RLM, Curtis MA, Dragunow M, Potempa J. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019 Jan 23;5(1):eaau3333. doi: 10.1126/sciadv.aau3333. eCollection 2019 Jan.

  PMID: 30746447 BACKGROUND

• Taghizadeh-Hesary, F.; Yoshino, N.; Mortha, A.; Taghizadeh-Hesary, F.; Roshanmehr, F.; Fiallos, J.; Tajra, E.; Bolanos, J.; Amaya, M.; Dang, J., et al. Economic burden of neurological disorders in an aging society (japan): A panel data analysis. . In ADBI Working Paper 1092, Asian Development Bank Institute: Tokyo, 2020.

  BACKGROUND

• Yon, M.J.Y.; Lam, Y.H.W.; Tsoi, K.H. Do economic and dental resources affect older persons' ohrqol? In IADR/PER 96th General Session & Exhibition, International Association for Dental Research. The Abstract's web site is located at http://www.iadr.org/: United States, 2018; Vol. 97, p no. 3003.

  BACKGROUND

• Miura, H.; Tano, T. Recent measures in geriatric oral health care in japan. J. Natl. Inst. Public Health 2019, 68, 8-16.

  BACKGROUND

• O'Connor, S. (2014). World will have 13 'super-aged'nations by 2020. Financial Times, 11.

  RESULT

MeSH Terms

Conditions

Oral Manifestations

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Kit Hon Tsoi, PhD

  Faculty of Dentistry, The University of Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2022
• First Posted: September 22, 2022
• Study Start: August 1, 2022
• Primary Completion: May 30, 2023
• Study Completion: May 30, 2023
• Last Updated: October 12, 2023

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF
• Time Frame: the data will be available after the results are released and published.
• Access Criteria: requested from the principal investigator via email: jkhtsoi@hku.hk

Locations

HK (1)