Oral Manifestations in Egyptian Children With Short Stature

NCT06372366 | Not Yet Recruiting

• 1 other identifier: Oral signs ,short stature
• Study Type: observational
• Target: 2
• Locations: 0 countries
• Sites: N/A

Brief Summary

Children with short stature have been reported to show a higher prevalence of enamel hypoplasia, delayed tooth eruption, and malocclusion compared to children of normal growth status

Conditions

Oral Manifestations; Short Stature

Outcome Measures

Primary Outcomes (4)

• Dental enamel defects

  using Aine's classification

  3 months

• Delayed dental eruption

  using Dental eruption table

  3 months

• Malocclusion

  using Angle classification

  3 months

• Dental caries experience

  using def+DMF

  3 months

Study Arms (2)

17children with short stature

17 normal children

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children aged from 6 to 12 years attending National Nutrition Institute will be included in the study according to the following criteria:

You may qualify if:

• - Egyptian children aged 6-12 years.
• \- Diagnosed with short stature (height-for-age \< -2 SD based on WHO standards).
• \- Diagnosed and confirmed by a pediatric endocrinologist.
• Controls:
• \- Age- and sex-matched children with normal height (height-for-age between -1 and +1 SD).
• \- Recruited from the same geographic and socioeconomic backgrounds.

You may not qualify if:

• Presence of syndromic conditions (e.g., Turner syndrome, Down syndrome).
• Chronic diseases (e.g., renal, cardiac, or endocrine conditions other than idiopathic short stature).
• Long-term medication use known to affect growth or oral development.

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Oral Manifestations; Dwarfism

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Bone Diseases, Developmental; Bone Diseases; Musculoskeletal Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal researcher (Dentist)

Study Record Dates

• First Submitted: April 14, 2024
• First Posted: April 18, 2024
• Study Start: December 15, 2025
• Primary Completion: March 15, 2026
• Study Completion: April 15, 2026
• Last Updated: December 2, 2025

Record last verified: 2025-07