Exercise Recovery From Persistent Depression: A Thematic Analysis

NCT05539495 | Unknown

• 1 other identifier: 22032
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Depression is a leading cause of disability worldwide and poses a large economic burden in the UK. There is evidence that exercise is beneficial in the management of depression and NICE now recommends group exercise programs as a treatment for people with mild and moderate-severe depression. Research shows that patients with severe depression are less likely to engage in exercise than patients with mild to moderate depression. There is little evidence, however, on the barriers and drivers to participation in such programs experienced by patients with depression; leading to uncertainty in the most effective way to implement these programs. We aim to analyse accounts of patients who have been referred to or participated in the Exercise Recovery Group (ERG), a group exercise program at the Nottingham Specialist Depression Service (NSDS). The NSDS is a tertiary unit where referred patients have suffered moderate-severe, persistent clinical depression. Eligible participants will be patients with persistent major depression who have agreed to referral to the ERG at the NSDS and who are able to provide informed consent. Participants will undergo a one-off 60 minute meeting via MS Teams, including an in-depth semi-structured interview on their experience as well as self-completion questionnaires assessing demographics, depression, anxiety and shame. Transcripts of the interviews will be subject to qualitative thematic analysis addressing questions on barriers and drivers of exercise treatment in depression; and the perceived impact of an exercise group on the individual participating. Themes will be developed to give an account of these questions, supported by anonymised quotes from the transcripts. The questionnaire data (on demographics, depression, anxiety, shame) will be used to characterise the group, in order to help assess directness of the evidence provided for other clinical populations; ultimately helping clinicians to implement exercise groups for depression that are acceptable for patients.

Conditions

Major Depressive Disorder; Depression Moderate; Depression Severe

Keywords

Exercise; Barriers; Facilitators

Outcome Measures

Primary Outcomes (1)

• What are the barriers and drivers to using exercise as a treatment for persistent major depression? via thematic analysis of semi-structured interview.

  Semi-structured interview transcripts will be subject to a qualitative thematic analysis with simple descriptive statistics (via demographic questionnaire, PHQ9, GAD7, and ESS) to characterise the sample and support any anonymised quotes. Analysis of interviews will use a standard Qualitative software package (NVivo version 12) to conduct thematic analysis through an iterative process of coding, organising coding into themes, reviewing themes, and generating a final thematic narrative with reference to the research question. We will use both deductive and inductive elements in the thematic analysis.

  12 months

Secondary Outcomes (2)

• How do these barriers and drivers operate at different stages of 'participation', including contemplation of group participation; and within group participation? via thematic analysis of semi-structured interview.

  12 months

• What is the perceived impact of an exercise group on the individual participating, including positive and negative effects? via thematic analysis of semi-structured interview.

  12 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with persistent major depression who have at least agreed to referral to the Exercise Recovery Group at the Nottingham Specialist Depression Service within the previous 24 months

You may qualify if:

• Patients with persistent major depression
• Patients who have at least agreed to referral to the Exercise Recovery Group within the previous 24 months
• Patients who are able to provide informed consent.

You may not qualify if:

• Patients with a main diagnosis of Bipolar Disorder.
• Patients who cannot speak fluently in English.
• Patients without an email account or access to an electronic device that could be used for the MS Teams meeting.
• Patients who are younger than 18-years-old. There is no upper age limit.

Sponsors & Collaborators

• University of Nottingham: lead
• Nottinghamshire Healthcare NHS Trust: collaborator

Study Sites (1)

Nottinghamshire Healthcare NHS Foundation Trust

Nottingham, Nottinghamshire, NG3 6AA, United Kingdom

Location

Related Publications (21)

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  PMID: 31389872 BACKGROUND

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  PMID: 27155287 BACKGROUND

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  BACKGROUND

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  BACKGROUND

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  BACKGROUND

MeSH Terms

Conditions

Depressive Disorder, Major; Motor Activity

Condition Hierarchy (Ancestors)

Depressive Disorder; Mood Disorders; Mental Disorders; Behavior

Study Officials

• Neil Nixon, BSc,MMedSci,MBBS,DM,FRCPsych

  University of Nottingham

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Neil Nixon, BSc,MMedSci,MBBS,DM,FRCPsych

CONTACT

000; neil.nixon@nottingham.ac.uk

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2022
• First Posted: September 14, 2022
• Study Start: September 1, 2022
• Primary Completion: December 1, 2022
• Study Completion: August 1, 2023
• Last Updated: September 14, 2022

Record last verified: 2022-09

Locations

GB (1)