Snapshot Rectumcarcinoom 2016

NCT05539417 | Completed

• 1 other identifier: 2020.366
• Study Type: observational
• Target: 3,107
• Locations: 0 countries
• Sites: N/A

Brief Summary

The treatment of rectal cancer is developing rapidly in the Netherlands, as well as internationally. This is accompanied by an increase in complexity of diagnosis and treatment, particularly when the tumor is located closer to the anorectal junction. Within these developments there is an important role for quality evaluation, where continuous feedback is able to improve care for rectal cancer in the Netherlands. By supplementing data from the Dutch ColoRectal Audit (DCRA) with additional data concerning diagnostics and treatment of rectal cancer patients operated in the year 2016, the Snapshot Rectumcarcinoom 2016 aimed to assess the improvement in surgical and oncological outcomes.

Conditions

Rectal Cancer

Outcome Measures

Primary Outcomes (2)

• How do different variables affect oncological and surgical outcomes?

  This study will evaluate development between 2011 and 2016 by comparing this cohort to the Snapshot 2011 study.

  2016-2020

• The variation in treatment and awareness of lateral lymph nodes in patients with rectal cancer.

  This study aims to assess the variation in treatment and the awareness of lateral lymph nodes in patients with rectal cancer. To increase awareness and improve current practices, MRI reassessment after training of radiologists will take place. Moreover, delineation training will be given to radiation oncologists. After these improvements in current practice, evaluation of this training will take place.

  2016-2020

Secondary Outcomes (3)

• Anastomotic leakage

  2016-2020

• Permanent stoma rate

  2016-2020

• Presence of presacral abscess

  2016-2020

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who underwent resection for primary rectal cancer in the Netherlands in 2016.

You may qualify if:

• Primary rectal cancer
• Operated in 2016 in a Dutch hospital
• Registred in the DCRA-register

You may not qualify if:

• Wait and see
• Resection for regrowth after wait and see

Sponsors & Collaborators

• Amsterdam UMC, location VUmc: lead

Related Publications (5)

• Ogura A, Konishi T, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, Lee IK, Lee HX, Uehara K, Lee P, Putter H, van de Velde CJH, Beets GL, Rutten HJT, Kusters M; Lateral Node Study Consortium. Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral Node Study of Patients With Low cT3/4 Rectal Cancer. J Clin Oncol. 2019 Jan 1;37(1):33-43. doi: 10.1200/JCO.18.00032. Epub 2018 Nov 7.

  PMID: 30403572 RESULT

• Ogura A, Konishi T, Beets GL, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, Lee IK, Lee HX, Uehara K, Lee P, Putter H, van de Velde CJH, Rutten HJT, Tuynman JB, Kusters M; Lateral Node Study Consortium. Lateral Nodal Features on Restaging Magnetic Resonance Imaging Associated With Lateral Local Recurrence in Low Rectal Cancer After Neoadjuvant Chemoradiotherapy or Radiotherapy. JAMA Surg. 2019 Sep 1;154(9):e192172. doi: 10.1001/jamasurg.2019.2172. Epub 2019 Sep 18.

  PMID: 31268504 RESULT

• van Geffen EGM, Verheij FS, Hazen SMJA, Sluckin TC, Consten ECJ, Dekker JT, Nederend J, Peeters KCMJ, de Wilt JHW, van Dieren S, Hompes R, Tuynman JB, Marijnen CAM, Tanis PJ, Kusters M; Dutch Snapshot Research Group. Oncological outcomes of planned and unplanned low Hartmann's procedure and restorative low anterior resection for rectal cancer: a population-based cross-sectional study. Tech Coloproctol. 2025 Nov 23;30(1):4. doi: 10.1007/s10151-025-03169-5.

  PMID: 41276685 DERIVED

• Moolenaar LR, van Geffen EGM, Hazen SJA, Sluckin TC, Beets GL, Leijtens JWA, Talsma AK, de Wilt JHW, Tanis PJ, Kusters M, Hompes R, Tuynman JB; Dutch Snapshot Research Group; Collaborators Snapshot Registry. Salvageable locoregional recurrence and stoma rate after local excision of pT1-2 rectal cancer - A nationwide cross-sectional cohort study. Eur J Surg Oncol. 2025 Jun;51(6):109623. doi: 10.1016/j.ejso.2025.109623. Epub 2025 Jan 23.

  PMID: 40009914 DERIVED

• Sluckin TC, Hazen SJA, Horsthuis K, Beets-Tan RGH, Antonisse IE, Berbee M, van Bockel LW, Boer AH, Ceha HM, Cnossen JS, Geijsen ED, den Hartogh MD, Hendriksen EM, Intven MPW, Leseman-Hoogenboom MM, Meijnen P, Muller K, Oppedijk V, Rozema T, Rutten H, Spruit PH, Stam TC, Velema LA, Verrijssen AE, Vos-Westerman J, Tanis PJ, Marijnen CAM, Kusters M; Dutch Snapshot Research Group. Coverage of Lateral Lymph Nodes in Rectal Cancer Patients with Routine Radiation Therapy Practice and Associated Locoregional Recurrence Rates. Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):422-433. doi: 10.1016/j.ijrobp.2023.04.013. Epub 2023 Apr 28.

  PMID: 37120027 DERIVED

MeSH Terms

Conditions

Rectal Neoplasms

Condition Hierarchy (Ancestors)

Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 9, 2022
• First Posted: September 14, 2022
• Study Start: January 1, 2016
• Primary Completion: December 31, 2016
• Study Completion: December 31, 2016
• Last Updated: September 16, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will share
• Time Frame: Starting after initial publication of data
• Access Criteria: Requests will be assessed by the study team