NCT05536661

Brief Summary

Clinical, prospective, comparative, controlled, single-blind study, on the signs and symptoms of dry eye before and after 3 days of playing video games with the use of artificial tears (Hyabak) versus no intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 4, 2019

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 7, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 7, 2019

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

September 7, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 13, 2022

Completed
Last Updated

September 13, 2022

Status Verified

September 1, 2022

Enrollment Period

3 days

First QC Date

September 7, 2022

Last Update Submit

September 9, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Standard Patient Evaluation of Eye Dryness (SPEED)

    Change in Standard Patient Evaluation of Eye Dryness (SPEED) score between study and control group (range 0-28, with higher scores indicative of dry eye disease symptoms)

    Between Day 1 and Day 3

Secondary Outcomes (7)

  • Conjunctival hyperemia measured with McMonnies Chapman scale

    Between Day 1 and Day 3

  • Tear Breakup Time (TBUT)

    Between Day 1 and Day 3

  • Conjunctival staining with lisamine green measured with Oxford scale

    Between Day 1 and Day 3

  • Corneal staining with fluorescein measured with Oxford scale

    Between Day 1 and Day 3

  • Schirmer I tear volume test

    Between Day 1 and Day 3

  • +2 more secondary outcomes

Study Arms (2)

Study group

EXPERIMENTAL

Preservative free Hyaluronic acid 0.15% artificial tear instilled in both eyes 4 times daily for 3 days

Other: Preservative free hyaluronic acid artificial tear

Control group

NO INTERVENTION

No artificial tear instilation

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • Participants in videogame convention planning to play video games for a minimum of 6 hours daily for the next 3 days.
  • Voluntarily accept to participate and sign informed consent form

You may not qualify if:

  • Ocular, nasolagrimal or palpebral active condition different from dry eye disease.
  • History of refractive surgery.
  • Visual acuity 0.5 or less in at least 1 eye.
  • History of systemic condition asociated to dry eye.
  • Use of systemic medication known to induce dry eye in the last 30 days.
  • Known allergy to hyaluronic acid.
  • Pregnant or lactating women.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dreamhack Convention

Valencia, 46035, Spain

Location

MeSH Terms

Conditions

Dry Eye Syndromes

Condition Hierarchy (Ancestors)

Lacrimal Apparatus DiseasesEye Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2022

First Posted

September 13, 2022

Study Start

July 4, 2019

Primary Completion

July 7, 2019

Study Completion

July 7, 2019

Last Updated

September 13, 2022

Record last verified: 2022-09

Data Sharing

IPD Sharing
Will not share

Locations