NCT03055897

Brief Summary

The objective of this study was to measure the temperature of the cornea and surrounding eye tissue temperature immediately after heating the eyelids with the iLux device using the protocol treatment profile. Eligible participants attended one treatment visit, with follow-up one day following the procedure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 3, 2016

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 17, 2016

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 18, 2016

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

February 10, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 16, 2017

Completed
3.8 years until next milestone

Results Posted

Study results publicly available

December 16, 2020

Completed
Last Updated

April 12, 2023

Status Verified

November 1, 2020

Enrollment Period

14 days

First QC Date

February 10, 2017

Results QC Date

November 18, 2020

Last Update Submit

April 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean Overall Maximum Temperature of the Cornea and Surrounding Eye Tissue Immediately Post-treatment

    Post-heating values were obtained by infrared camera for each participant. The cornea, the eyelid, and the surface tissue surrounding the eye were measured. Both eyes contributed to the analysis. No formal hypothesis testing was specified.

    Day 0 immediately post-treatment

Study Arms (1)

iLux 2020 System

EXPERIMENTAL

Meibomian gland treatment (Day 0) according to instructions for use (IFU)/User Manual

Device: iLux 2020 System

Interventions

Medical device that applies localized heat and pressure therapy to the eyelid in order to express melted meibum from obstructed glands

iLux 2020 System

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- Sign written informed consent prior to study participation

You may not qualify if:

  • History of ocular surgery within 1 year
  • Active ocular infection
  • Ocular surface abnormality; lid surface abnormalities
  • Pregnant, nursing or not utilizing adequate birth control measures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

TearFilm Innovations Investigative Site

Encinitas, California, 92924, United States

Location

MeSH Terms

Conditions

Meibomian Gland DysfunctionDry Eye Syndromes

Condition Hierarchy (Ancestors)

Eyelid DiseasesEye DiseasesLacrimal Apparatus Diseases

Results Point of Contact

Title
Senior CDMA Project Lead, CDMA Ocular Health
Organization
Alcon Research, LLC

Study Officials

  • Sr. CDMA Project Lead, CDMA Ocular Health

    Alcon Research, LLC

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2017

First Posted

February 16, 2017

Study Start

May 3, 2016

Primary Completion

May 17, 2016

Study Completion

May 18, 2016

Last Updated

April 12, 2023

Results First Posted

December 16, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations