Strokecopilot: A Precision Medicine Tool in the Stroke Emergency

NCT05534295 | Unknown

• 1 other identifier: 8589
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

Ischemic stroke or cerebral infarction (CI) is an immediate emergency affecting approximately 100,000 - 150,000 patients each year in France and is managed in the neurovascular intensive care unit (NICU). Recanalization treatments can prevent disability, but patients must be carefully selected. Knowledge in this field is evolving rapidly, which tends to make management more complex and personalized. In addition, the permanence of thrombolysis channels involves neurologists of all expertise. Decision support tools are desirable to enable precision medicine in stroke. Strokecopilot is a web application developed by the principal investigator. Its algorithm contextualizes the patient in a set of evidence-based medicine references (recommendations and clinical trials) and gives the result of their cross-referencing to the user to indicate theoretical indications for intravenous thrombolysis and mechanical thrombectomy.

Conditions

Cerebrovascular Accident (CVA)

Keywords

cerebrovascular accident (CVA); Ischemic stroke; thrombolysis channels; intravenous thrombolysis; mechanical thrombectomy

Outcome Measures

Primary Outcomes (1)

• Retrospective analysis of thrombolysis data for the development of an algorithm to detect thrombolysis

  Files analysed retrospectively from January 01, 2017 to December 31, 2021 will be examined

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient (\>18 years old) admitted to the thrombolysis unit of the University Hospital of Strasbourg

You may qualify if:

• \- Adult patient (\>18 years old) admitted to the thrombolysis unit of the University Hospital of Strasbourg from January 01, 2017 to December 31, 2021

You may not qualify if:

• \- Subjects who have expressed their opposition to the use of their data for scientific research purposes.

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service : Unité Neurovasculaire - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Stroke; Ischemic Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Valérie WOLFF, MD, PhD

  Service : Unité Neurovasculaire - CHU de Strasbourg - France

  PRINCIPAL INVESTIGATOR

• Stanislas DEMUTH, MD

  Service : Unité Neurovasculaire - CHU de Strasbourg - France

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Valérie WOLFF, MD, PhD

CONTACT

33 3 88 12 85 19; valerie.wolff@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 2, 2022
• First Posted: September 9, 2022
• Study Start: May 10, 2022
• Primary Completion: December 1, 2023
• Study Completion: December 31, 2023
• Last Updated: December 13, 2023

Record last verified: 2023-12

Locations

FR (1)